Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129040 | 1.00 | SLC6A3 (0.38) | SLC6A3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8171321 | 1.00 | SLC6A3 (0.38) | SLC6A3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7036436 | 1.00 | SLC6A3 (0.38) | SLC6A3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6359164 | 1.00 | SLC6A3 (0.38) | SLC6A3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6363469 | 0.88 | SLC6A3 (0.41) | SLC6A3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6358601 | 0.88 | SLC6A3 (0.41) | SLC6A3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7039764 | 0.88 | SLC6A3 (0.41) | SLC6A3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6359667 | 0.88 | SLC6A3 (0.41) | SLC6A3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6357046 | 0.83 | SLC6A3 (0.57) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7122230 | 0.83 | SLC6A3 (0.57) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1493744-A1 | Tropane analogs and methods for inhibition of monoamine transport | ORGANIX, INC. (US) | 2005-01-05 | — | — | EP | disclosed |
| EP-0996619-B1 | TROPANE ANALOGS AND METHODS FOR INHIBITION OF MONOAMINE TRANSPORT | ORGANIX INC (US) | 2005-01-05 | — | — | EP | disclosed |