Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | SHBG | P04278 | 3/20 | 0.70 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.70 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | PGR | P06401 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20342396 | 1.00 | ALDH1A1 (0.70) | ALDH1A1SHBGSERPINA6SLC22A1THRB | |
| SCHEMBL7891346 | 0.89 | ALDH1A1 (0.72) | ALDH1A1SHBGSERPINA6SLC22A1THRB | |
| SCHEMBL5973336 | 0.89 | ALDH1A1 (0.72) | ALDH1A1SHBGSERPINA6SLC22A1THRB | |
| SCHEMBL2838231 | 0.89 | ALDH1A1 (0.68) | ALDH1A1SHBGSERPINA6SLC22A1THRB | |
| SCHEMBL7518658 | 0.88 | ALDH1A1 (0.67) | ALDH1A1SHBGSERPINA6SLC22A1THRB | |
| SCHEMBL13372738 | 0.88 | ALDH1A1 (0.67) | ALDH1A1SHBGSERPINA6SLC22A1THRB | |
| SCHEMBL2832494 | 0.87 | ALDH1A1 (0.69) | ALDH1A1SHBGSERPINA6SLC22A1THRB | |
| SCHEMBL13216858 | 0.87 | ALDH1A1 (0.69) | ALDH1A1SHBGSERPINA6SLC22A1THRB | |
| SCHEMBL11144395 | 0.86 | ALDH1A1 (0.65) | ALDH1A1SHBGSERPINA6SLC22A1THRB | |
| SCHEMBL8396003 | 0.84 | ALDH1A1 (0.65) | ALDH1A1SHBGSERPINA6SLC22A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009801-A1 | Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one | PETERS RICHARD H (US) | 2005-01-13 | — | — | US | claimed |
| WO-2001058919-A9 | SYNTHESIS OF ANTI-ESTROGENIC AND OTHER THERAPEUTIC STEROIDS FROM 21-HYDROXY-19-NORPREGNA-4-EN-3-ONE | STANFORD RES INST INT (US) | 2002-01-03 | — | — | WO | claimed |
| US-20010039269-A1 | Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one | SRI INTERNATIONAL | 2001-11-08 | — | — | US | claimed |
| WO-2001058919-A2 | SYNTHESIS OF ANTI-ESTROGENIC AND OTHER THERAPEUTIC STEROIDS FROM 21-HYDROXY-19-NORPREGNA-4-EN-3-ONE | SRI INTERNATIONAL (US) | 2001-08-16 | — | — | WO | claimed |
| EP-1163259-A1 | 14.BETA.,17-ALPHA-HYDROXYMETHYLANDROSTANE DERIVATIVES AS ANDROGENS | Akzo Nobel N.V. (NL) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000053619-A1 | 14.BETA., 17-ALPHA-HYDROXYMETHYLANDROSTANE DERIVATIVES AS ANDROGENS | AKZO NOBEL N.V. (NL) | 2000-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039269-A1 | Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one | NR5A1, HSD17B11, CYP17A1 | ALDH1A1 1199/4885SHBG 10/4885SERPINA6 745/4885 |
| US-20050009801-A1 | Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one | CYP17A1, NR5A1, HSD17B11 | ALDH1A1 1086/4885SHBG 10/4885SERPINA6 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.