SCHEMBL6357397

SCHEMBL6357397

c1ccc(Oc2ccc(Sc3ccc(Oc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 8/20 0.63
TSHR P16473 1/20 0.63
NR1H2 P55055 1/20 0.54
BAX Q07812 1/20 0.54
MAOA P21397 1/20 0.54
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
GSTP1 P09211 1/20 0.45
SOS1 Q07889 1/20 0.45
CA9 Q16790 1/20 0.45
PARP10 Q53GL7 1/20 0.45
PLA2G2A P14555 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SCN4A P35499 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NLRP3 Q96P20 1/20 0.43
SRD5A2 P31213 1/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12871225 1.00 LTA4H (0.63) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL20367129 0.97 LTA4H (0.60) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL3285418 0.95 LTA4H (0.55) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL8749832 0.92 LTA4H (0.67) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL11587543 0.89 LTA4H (0.75) LTA4HTSHRNR1H2BAXMAOA
Diphenylsulfane SCHEMBL11418454 0.88 LTA4H (0.55) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL9557550 0.87 MAOB (0.48) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL9556964 0.86 LTA4H (0.52) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL1127464 0.84 LTA4H (0.44) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL20367054 0.84 SLC6A4 (0.47) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041153-B Direct cross coupling method of aryl thioether and aryl bromine 南京工业大学 2024-05-24 CN claimed
CN-116041153-A Direct cross coupling method of aryl thioether and aryl bromine 南京工业大学 2023-05-02 CN claimed
US-4393241-A Synthesis of alkoxy and phenoxy substituted aryl sulfides CELANESE CORPORATION (US) 1983-07-12 US claimed
JP-1033128-A None JP disclosed
JP-1182320-A None JP disclosed
CN-116041153-B Direct cross coupling method of aryl thioether and aryl bromine 南京工业大学 2024-05-24 CN disclosed
CN-114478150-B S-deuterated methyl-aryl sulfonyl thioester compound and synthetic method and application thereof 浙江工业大学 2024-04-09 CN disclosed
CN-116041153-A Direct cross coupling method of aryl thioether and aryl bromine 南京工业大学 2023-05-02 CN disclosed
CN-114478150-A S-deuterated methyl-aryl sulfonyl thioester compound and synthesis method and application thereof 浙江工业大学 2022-05-13 CN disclosed
EP-3189099-B1 HYDROXYBENZOPHENONE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME SOLVAY SPECIALTY POLYMERS USA (US) 2018-07-11 EP disclosed
US-20160251545-A1 POLYIMIDE-BASED SOLUTION AND POLYIMIDE-BASED FILM PRODUCED USING SAME LG CHEM, LTD. (KR) 2016-09-01 US disclosed
US-4698448-A Method for making aromatic phosphorus compounds ROHM GMBH (DE) 1987-10-06 US disclosed
EP-0070147-B1 PREPARATION OF POLY(ARYLENE) KETONES RAYCHEM CORPORATION (a California corporation) (US) 1985-10-16 EP disclosed
US-4547553-A CROSSLINKED SOLVENT RESISTANT THERMOPLASTIC RESIN THE BOEING COMPANY (US) 1985-10-15 US disclosed
US-4393241-A Synthesis of alkoxy and phenoxy substituted aryl sulfides CELANESE CORPORATION (US) 1983-07-12 US disclosed
US-4375427-A DOPES, POLYTHIOETHERS ALLIED CORPORATION (US) 1983-03-01 US disclosed
EP-0070147-A1 Preparation of poly(arylene) ketones RAYCHEM CORPORATION (a California corporation) (US) 1983-01-19 EP disclosed
US-4361693-A Preparation of poly(arylene ketones) using thio- and dithiocarbonic acid derivatives RAYCHEM CORPORATION (US) 1982-11-30 US disclosed
EP-0031444-A2 Electronically conductive organic thermoplastic composition ALLIED CORPORATION (US) 1981-07-08 EP disclosed
US-3939084-A Functional fluid compositions containing substituted pyrimidines MONSANTO COMPANY (US) 1976-02-17 US disclosed