SCHEMBL1127464

SCHEMBL1127464

Sc1ccc(Oc2ccc(Sc3ccccc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.44
TSHR P16473 1/20 0.44
MAOA P21397 3/20 0.41
MAOB P27338 2/20 0.41
NR1H2 P55055 1/20 0.40
BAX Q07812 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 2/20 0.38
HPGD P15428 1/20 0.38
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
STS P08842 1/20 0.35
SLC6A4 P31645 1/20 0.35
MMP3 P08254 1/20 0.35
MMP8 P22894 1/20 0.35
MMP13 P45452 1/20 0.35
GSTP1 P09211 1/20 0.34
SOS1 Q07889 1/20 0.34
CA9 Q16790 1/20 0.34
PARP10 Q53GL7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3285418 0.89 LTA4H (0.55) LTA4HTSHRMAOAMAOBNR1H2
SCHEMBL20367129 0.87 LTA4H (0.60) LTA4HTSHRMAOAMAOBNR1H2
SCHEMBL544383 0.87 MAOA (0.50) TSHRMAOAMAOBNR1H2SMN1; SMN2
SCHEMBL25895028 0.87 MAOA (0.50) TSHRMAOAMAOBNR1H2SMN1; SMN2
Hydrochloric Acid SCHEMBL9007558 0.84 MAOA (0.48) TSHRMAOAMAOBNR1H2SMN1; SMN2
SCHEMBL12871225 0.84 LTA4H (0.63) LTA4HTSHRMAOANR1H2BAX
SCHEMBL6357397 0.84 LTA4H (0.63) LTA4HTSHRMAOANR1H2BAX
Fluoride SCHEMBL27764069 0.82 MAOA (0.46) TSHRMAOAMAOBNR1H2SMN1; SMN2
Diphenylether SCHEMBL8749832 0.82 LTA4H (0.67) LTA4HTSHRMAOAMAOBNR1H2
SCHEMBL487535 0.82 LTA4H (0.67) LTA4HTSHRMAOAMAOBNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024579-B2 Curable liquid composition, particulate filler, and compound TOKYO OHKA KOGYO CO., LTD. (JP) 2024-07-02 US disclosed
CN-113402657-B Photopolymerization initiator containing aryl iodonium salt for dental photocurable composition 株式会社松风 2024-06-11 CN disclosed
CN-112470551-B Sealing agent for organic electroluminescent display element 电化株式会社 2024-05-14 CN disclosed
CN-113227159-B Composition and method for producing the same 电化株式会社 2024-04-19 CN disclosed
CN-110007557-B Curable composition, film, optical film, light-emitting display element panel, and light-emitting display device 东京应化工业株式会社 2024-04-12 CN disclosed
EP-3881818-B1 DENTAL PHOTOCURABLE COMPOSITIONS COMPRISING PHOTOPOLYMERIZATION INITIATOR COMPRISING AN ARYLIODONIUM SALT SHOFU KK (JP) 2024-03-06 EP disclosed
US-20240045330-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-08 US disclosed
CN-117510794-A Composition and method for producing the same 电化株式会社 2024-02-06 CN disclosed
US-20240027901-A1 PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION USING SAME SAN-APRO LTD. (JP) 2024-01-25 US disclosed
CN-117420731-A Negative photosensitive composition and pattern forming method 东京应化工业株式会社 2024-01-19 CN disclosed
US-20110300482-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION SAN-APRO, LTD (JP) 2011-12-08 US disclosed
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF SAN-APRO LIMITED (JP) 2011-02-17 US disclosed
EP-2284165-A1 PHOSPHONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION San-Apro Limited (JP) 2011-02-16 EP disclosed
EP-2239295-A2 Radiation-curable silicone composition Shin-Etsu Chemical Co., Ltd. (JP) 2010-10-13 EP disclosed
US-20100255417-A1 RADIATION-CURABLE SILICONE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-10-07 US disclosed
US-7709598-B2 Fluorinated alkyl fluorophoshoric acid salts of onium and transition metal complex SAN-APRO LIMITED (JP) 2010-05-04 US disclosed
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE SAN-APRO LIMITED (JP) 2009-06-25 US disclosed
EP-1953139-A1 METHOD FOR PRODUCING FLUORINATED SULFONIUM ALKYLFLUOROPHOSPHATE San-Apro Ltd. (JP) 2008-08-06 EP disclosed
US-20070225458-A1 Novel Fluorinated Alkyl Fluorophosphoric Acid Salts of Onium and Ttransition Metal Complex SAN-APRO LIMITED (JP) 2007-09-27 US disclosed
EP-1752463-A1 NOVEL FLUORINATED ALKYLFLUOROPHOSPHORIC ACID SALT OF ONIUM AND TRANSITION METAL COMPLEX San-Apro Limited (JP) 2007-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240027901-A1 PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION USING SAME ATIC, MAP1LC3C, TYR LTA4H 1851/4885TSHR 2891/4885MAOA 580/4885
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE ARSA, SCO2, DOHH LTA4H 2313/4885TSHR 158/4885MAOA 2326/4885
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF ARSA, ASIC1, TST LTA4H 3043/4885TSHR 1928/4885MAOA 4685/4885
US-20070225458-A1 Novel Fluorinated Alkyl Fluorophosphoric Acid Salts of Onium and Ttransition Metal Complex AS3MT, TTR, PFAS LTA4H 4646/4885TSHR 753/4885MAOA 2341/4885
US-20110300482-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION ASIC1, H1-0, IK LTA4H 2072/4885TSHR 3005/4885MAOA 4359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.