⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2212951 | 0.73 | — | — | |
| SCHEMBL222639 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL7774252 | 0.70 | — | — | |
| SCHEMBL1931721 | 0.67 | APLNR (0.35) | — | |
| SCHEMBL4211012 | 0.67 | — | — | |
| SCHEMBL124081 | 0.67 | — | — | |
| SCHEMBL60402 | 0.67 | — | — | |
| SCHEMBL1162544 | 0.67 | — | — | |
| SCHEMBL707678 | 0.67 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL6507946 | 0.65 | CA2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106488915-A | Cyclopropylamine as LSD1 inhibitor | 因赛特公司 | 2017-03-08 | — | — | CN | disclosed |
| US-20050234090-A1 | Modulators of chemokine receptor activity | PFIZER INC | 2005-10-20 | — | — | US | disclosed |
| US-6821964-B2 | FOR PROPHYLAXIS AND THERAPY OF DISEASES ASSOCIATED WITH MONOCYTE ACCUMULATION, LYMPHOCYTE ACCUMULATION OR LEUCOCYTE ACCUMULATION | PFIZER INC | 2004-11-23 | — | — | US | disclosed |
| EP-1368354-A1 | MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Pfizer Products Inc. (US) | 2003-12-10 | — | — | EP | disclosed |
| US-20030008893-A1 | Modulators of chemokine receptor activity | COLON-CRUZ ROBERTO (US) | 2003-01-09 | — | — | US | disclosed |
| WO-2002070523-A1 | MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | PFIZER PRODUCTS INC. (US) | 2002-09-12 | — | — | WO | disclosed |