Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12505430 | 0.87 | APP (0.56) | MRGPRX4ENPP2MAPK1MAPTTDP1 | |
| SCHEMBL6553017 | 0.87 | HPGD (0.66) | MRGPRX4ENPP2MAPTTDP1NFKB1 | |
| SCHEMBL15613732 | 0.83 | MRGPRX4 (0.68) | MRGPRX4ENPP2MAPK1MAPTTDP1 | |
| SCHEMBL13192152 | 0.83 | ATM (0.52) | MRGPRX4MAPK1L3MBTL1NPC1RAB9A | |
| SCHEMBL21945455 | 0.82 | MRGPRX4 (0.67) | MRGPRX4ENPP2MAPTTDP1NFKB1 | |
| SCHEMBL12505427 | 0.82 | PARP1 (0.64) | MRGPRX4MEN1NPC1RAB9AKMT2A | |
| SCHEMBL13192629 | 0.82 | LMNA (0.62) | MAPTL3MBTL1MEN1RAB9AKMT2A | |
| SCHEMBL6359071 | 0.81 | MRGPRX4 (0.51) | MRGPRX4ENPP2NPC1DRD2DRD1 | |
| SCHEMBL10562035 | 0.79 | LTA4H (0.69) | ENPP2MAPK1MAPTNFKB1MEN1 | |
| SCHEMBL13192251 | 0.78 | BRD4 (0.76) | MAPTTDP1L3MBTL1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317068-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY | 2021-10-14 | — | — | US | disclosed |
| US-11072576-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2021-07-27 | — | — | US | disclosed |
| US-20190345094-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY | 2019-11-14 | — | — | US | disclosed |
| US-10385005-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2019-08-20 | — | — | US | disclosed |
| US-10000443-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2018-06-19 | — | — | US | disclosed |
| US-10000443-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2018-06-19 | — | — | US | disclosed |
| US-20160137585-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY (US) | 2016-05-19 | — | — | US | disclosed |
| US-9181162-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2015-11-10 | — | — | US | disclosed |
| US-20120121536-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317068-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | MRGPRX4 3273/4885ENPP2 1432/4885MAPK1 1094/4885 |
| US-20160137585-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | MRGPRX4 3273/4885ENPP2 1432/4885MAPK1 1094/4885 |
| US-10385005-B2 | Compositions and methods for glucose transport inhibition | SLC2A1, SLC2A4, SLC2A3 | MRGPRX4 3273/4885ENPP2 1432/4885MAPK1 1094/4885 |
| US-20190345094-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | MRGPRX4 3273/4885ENPP2 1432/4885MAPK1 1094/4885 |
| US-11072576-B2 | Compositions and methods for glucose transport inhibition | SLC2A1, SLC2A4, SLC2A3 | MRGPRX4 3273/4885ENPP2 1432/4885MAPK1 1094/4885 |
| US-20120121536-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | MRGPRX4 3273/4885ENPP2 1432/4885MAPK1 1094/4885 |
| US-10000443-B2 | Compositions and methods for glucose transport inhibition | SLC2A1, SLC2A4, SLC2A3 | MRGPRX4 3273/4885ENPP2 1432/4885MAPK1 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.