Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 11/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 10/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.44 |
| ▸ | LMNA | P02545 | 7/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | PIP4K2C | Q8TBX8 | 3/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CLK3 | P49761 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2369002 | 0.86 | ESR1 (0.48) | CYP1A2CYP2D6CYP3A4CLK4MAPK1 | |
| SCHEMBL2368333 | 0.83 | TSHR (0.43) | CYP1A2CYP2D6CYP3A4CLK4MAPK1 | |
| SCHEMBL2369291 | 0.82 | CYP1A2 (0.41) | CYP1A2CYP2D6CYP3A4CLK4MAPK1 | |
| SCHEMBL2368958 | 0.82 | CYP1A2 (0.41) | CYP1A2CYP2D6CYP3A4CLK4MAPK1 | |
| SCHEMBL6360222 | 0.82 | TNF (0.41) | MAPK1LMNAPIP4K2CMEN1KMT2A | |
| SCHEMBL2368351 | 0.81 | CCNE2 (0.41) | CYP1A2CYP2D6CYP3A4CLK4MAPK1 | |
| SCHEMBL2368616 | 0.80 | MEN1 (0.42) | CYP1A2CYP2D6CYP3A4CLK4MAPK1 | |
| SCHEMBL3383460 | 0.79 | PRKCZ (0.43) | CYP1A2CYP2D6CYP3A4CLK4MAPK1 | |
| SCHEMBL2369261 | 0.79 | SMN1; SMN2 (0.43) | CYP1A2CYP2D6CYP3A4CLK4MAPK1 | |
| SCHEMBL3383464 | 0.75 | CLK4 (0.37) | CYP1A2CYP2D6CYP3A4CLK4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026935-A1 | Compounds | XENTION DISCOVERY LTD. | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026935-A1 | Compounds | KCNJ11, KCNJ1, KCNH1 | CYP1A2 226/4885CYP2D6 225/4885CYP3A4 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.