Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL8356451 | 0.90 | CES2 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Hexanoate SCHEMBL9462906 | 0.90 | CES2 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Stearic Acid SCHEMBL11777658 | 0.89 | CES2 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Benzoyl Peroxide SCHEMBL21612074 | 0.86 | LMNA (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1816 | 0.83 | LMNA (0.67) | LMNAL3MBTL1MAPTTDP1F2 | |
| Hydrogen Peroxide SCHEMBL2929887 | 0.83 | LMNA (0.67) | LMNAL3MBTL1MAPTTDP1F2 | |
| Hydrogen Peroxide SCHEMBL11489043 | 0.83 | LMNA (0.67) | LMNAL3MBTL1MAPTTDP1F2 | |
| Benzene SCHEMBL10686034 | 0.83 | LMNA (0.67) | LMNAL3MBTL1MAPTTDP1F2 | |
| SCHEMBL27265493 | 0.83 | LMNA (0.67) | LMNAL3MBTL1MAPTTDP1F2 | |
| Butyric Acid SCHEMBL29789564 | 0.83 | LMNA (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050042268-A1 | Pharmaceutical composition and method for transdermal drug delivery | PERRIGO ISRAEL PHARMACEUTICALS LTD. (IL) | 2005-02-24 | — | — | US | disclosed |
| US-20050025833-A1 | Pharmaceutical composition and method for transdermal drug delivery | PERRIGO ISRAEL PHARMACEUTICALS LTD. (IL) | 2005-02-03 | — | — | US | disclosed |
| US-20050020552-A1 | Pharmaceutical composition and method for transdermal drug delivery | PERRIGO ISRAEL PHARMACEUTICALS LTD. (IL) | 2005-01-27 | — | — | US | disclosed |