Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Perchlorate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL4388399 | 1.00 | CA5A (0.61) | CA5ACA5BALDH1A1TDP1MEN1 | |
| Perchlorate SCHEMBL8393252 | 0.96 | CA5A (0.57) | CA5ACA5BALDH1A1TDP1MEN1 | |
| Perchlorate SCHEMBL8393262 | 0.96 | CA5A (0.57) | CA5ACA5BALDH1A1TDP1MEN1 | |
| Perchlorate SCHEMBL8393276 | 0.96 | CA5A (0.57) | CA5ACA5BALDH1A1TDP1MEN1 | |
| Perchlorate SCHEMBL31252824 | 0.96 | — | — | |
| Perchlorate SCHEMBL574182 | 0.96 | — | — | |
| Perchlorate SCHEMBL8393279 | 0.93 | CA5A (0.53) | CA5ACA5BALDH1A1TDP1MEN1 | |
| Perchlorate SCHEMBL6331805 | 0.93 | CA5A (0.53) | CA5ACA5BALDH1A1TDP1MEN1 | |
| Perchlorate SCHEMBL9436355 | 0.93 | CA5A (0.53) | CA5ACA5BALDH1A1TDP1 | |
| Perchlorate SCHEMBL1629189 | 0.92 | CA5A (0.61) | CA5ACA5BALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605167-B1 | Spontaneous combustion mixtures comprising oxidizers and metal fuels encapsulated in thermoplastic elastomers, used in inflatable protective devices such as automobile air bags | TRW INC. | 2003-08-12 | — | — | US | claimed |
| US-6896751-B2 | Energetics binder of fluoroelastomer or other latex | UNIVERSAL PROPULSION COMPANY, INC. (US) | 2005-05-24 | — | — | US | disclosed |
| US-20040226638-A1 | Energetics binder of fluoroelastomer or other latex | UNIVERSAL PROPULSION COMPANY, INC. | 2004-11-18 | — | — | US | disclosed |
| WO-1997024299-A1 | GASSER COMPOSITION AND METHOD OF GASSING | ORICA AUSTRALIA PTY LTD (AU) | 1997-07-10 | — | — | WO | disclosed |
| EP-0109747-A2 | A method and means for making an explosive in the form of an emulsion | AECI LIMITED (ZA) | 1984-05-30 | — | — | EP | disclosed |