Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Perchlorate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL8393279 | 0.97 | CA5A (0.53) | CA5ACA5BALDH1A1TDP1MEN1 | |
| Perchlorate SCHEMBL4388399 | 0.96 | CA5A (0.61) | CA5ACA5BALDH1A1TDP1MEN1 | |
| Perchlorate SCHEMBL6358259 | 0.96 | CA5A (0.61) | CA5ACA5BALDH1A1TDP1MEN1 | |
| Perchlorate SCHEMBL8393252 | 0.93 | CA5A (0.57) | CA5ACA5BALDH1A1TDP1MEN1 | |
| Perchlorate SCHEMBL8393276 | 0.93 | CA5A (0.57) | CA5ACA5BALDH1A1TDP1MEN1 | |
| Perchlorate SCHEMBL31252824 | 0.93 | — | — | |
| Perchlorate SCHEMBL574182 | 0.93 | — | — | |
| Perchlorate SCHEMBL6331805 | 0.90 | CA5A (0.53) | CA5ACA5BALDH1A1TDP1MEN1 | |
| Perchlorate SCHEMBL9436355 | 0.90 | CA5A (0.53) | CA5ACA5BALDH1A1TDP1 | |
| Perchlorate SCHEMBL7175167 | 0.89 | CA5A (0.61) | CA5ACA5BALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004410-A | AIR BAGS FOR AUTOMOBILES | TRW INC. (US) | 1999-12-21 | — | — | US | disclosed |