SCHEMBL6358281

SCHEMBL6358281

Cc1nc2nc(N)nc(Cl)c2[nH]1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.58
DPP4 P27487 1/20 0.52
CCNA2 P20248 1/20 0.43
CDK2 P24941 1/20 0.43
ADORA2A P29274 4/20 0.37
ADORA1 P30542 4/20 0.37
CSNK2A1 P68400 1/20 0.36
ADORA3 P0DMS8 2/20 0.35
ALDH1A1 P00352 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PDPK1 O15530 1/20 0.33
GDA Q9Y2T3 1/20 0.33
MAP3K5 Q99683 1/20 0.33
PNP P00491 1/20 0.32
HSP90B1 P14625 2/20 0.32
TRAP1 Q12931 2/20 0.32
HSP90AA1 P07900 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29495248 0.79 NUDT1 (0.39) NUDT1ADORA2AADORA1CSNK2A1ADORA3
SCHEMBL16499673 0.79 NUDT1 (0.39) NUDT1ADORA2AADORA1CSNK2A1ADORA3
SCHEMBL3158628 0.79 DPP4 (0.50) NUDT1DPP4ADORA2AADORA1PDPK1
SCHEMBL6356987 0.79 PNP (0.54) NUDT1DPP4ADORA2AADORA1CSNK2A1
SCHEMBL2634662 0.79 NUDT1 (0.61) NUDT1CCNA2CDK2PDPK1GDA
SCHEMBL1290911 0.79 NUDT1 (0.61) NUDT1DPP4CCNA2CDK2ADORA2A
SCHEMBL8080150 0.77 DPP4 (0.44) NUDT1DPP4ADORA2AADORA1L3MBTL1
SCHEMBL8216346 0.76 NUDT1 (0.58) NUDT1DPP4CCNA2CDK2ADORA2A
SCHEMBL7616444 0.76 NUDT1 (0.58) NUDT1DPP4CCNA2CDK2ADORA2A
SCHEMBL6363421 0.76 DPP4 (0.43) NUDT1DPP4ADORA2AADORA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101380308-A Anticancer sustained-release preparation loaded with anti-cancer medicine and synergist thereof JINAN SHUAIHUA PHARMACEUTICAL (CN) 2009-03-11 CN claimed
CN-101045059-A Anticarcinogen composition carried with both nitrosourea type medicine and guanine analog SHUAIHUA MEDICAL SCIENCE & TEC (CN) 2007-10-03 CN claimed
CN-101023925-A Anti-cancer composition containing chemical-therapy synergistic agent JINAN KANGQUAN MEDICINE SCIENC (CN) 2007-08-29 CN claimed
CN-101011352-A Anti-cancer composition loading both mtrosourea medicament and guanopterin analog JINAN SHUAIHUA PHARM TECHNOLOG (CN) 2007-08-08 CN claimed
CN-100998555-A Slow-release anticarcinogen containing vasoinhibitor SHUAIHUA MEDICINE SCIENCE CO L (CN) 2007-07-18 CN claimed
CN-1973821-A Medicine composition containing both anticancer medicine and its synergist SHANDONG LANJIN BIOENGINEERING (CN) 2007-06-06 CN claimed
CN-1969828-A Anticancer sustained release injection containing mesenchyme hydrolytic agent JINAN KANGQUAN PHARMACEUTICAL (CN) 2007-05-30 CN claimed
CN-1969821-A Anticancer sustained-release agent carrying anticancer drug and synergist JINAN SHUAIHUA MEDICAL TECHNOL (CN) 2007-05-30 CN claimed
CN-1927179-A Compound recipe anticancer slow release injection comprising tetrazole violet JINAN SHUAIHUA PHARMACEUTICAL (CN) 2007-03-14 CN claimed
CN-1887260-A Slow released compound anticancer injection containing clorfarabine JINAN KANGQUAN MEDICINE SCI TE (CN) 2007-01-03 CN claimed
CN-1846685-A Slow-released injection containing bendamustine and its synergist JINAN SHUAIHUA MEDICINE SCI TE (CN) 2006-10-18 CN claimed
CN-1846674-A Slow released anticancer injection JINAN SHUIHUA MEDICINE SCI TEC (CN) 2006-10-18 CN claimed
CN-1733306-A Anticancer implantation agent containing blood vessel inhibitor and guanine similarities KONG QINGZHONG (CN) 2006-02-15 CN claimed
CN-1679947-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679946-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679945-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679936-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679951-A Medicinal composition for tumor body LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679944-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1628852-A Anti solid tumor medicine composition KONG QINGZHONG (CN) 2005-06-22 CN claimed