Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NR2E1 | Q9Y466 | 5/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | HTR6 | P50406 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | SCN1A | P35498 | 2/20 | 0.49 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365539 | 0.90 | CYP1A2 (0.73) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL9330063 | 0.90 | CYP1A2 (0.73) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL11871935 | 0.86 | CYP1A2 (0.56) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL14901592 | 0.82 | ADRB2 (0.49) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL14901599 | 0.81 | CYP1A2 (0.51) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL12999565 | 0.81 | CYP1A2 (0.57) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL10472270 | 0.81 | HTR1A (0.73) | CYP1A2KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL11867441 | 0.79 | ADRB2 (0.44) | CYP1A2KDM4ENR2E1ADRB2ADRB1 | |
| SCHEMBL4231217 | 0.78 | TLR4 (0.50) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL11468344 | 0.78 | CYP1A2 (0.41) | CYP1A2CYP2C19KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030149219-A1 | Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom | BORIACK CLINTON J (US) | 2003-08-07 | — | — | US | claimed |
| US-6534621-B2 | Epoxidizing an alpha-halohydrin intermediate produced from an in situ halide substitution-deesterification of an alpha-hydroxy ester derivative | DOW GLOBAL TECHNOLOGIES INC. | 2003-03-18 | — | — | US | claimed |
| US-20020045707-A1 | Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom | DOW GLOBAL TECHNOLOGIES INC. | 2002-04-18 | — | — | US | claimed |
| US-20050165201-A1 | Epoxidizing an alpha-halohydrin intermediate from a halide substitution-deesterification of an alpha -hydroxy ester derivative obtained by the coupling reaction of a phenol and a glycidyl ester | BORIACK CLINTON J (US) | 2005-07-28 | — | — | US | disclosed |
| US-20030149219-A1 | Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom | BORIACK CLINTON J (US) | 2003-08-07 | — | — | US | disclosed |
| US-6534621-B2 | Epoxidizing an alpha-halohydrin intermediate produced from an in situ halide substitution-deesterification of an alpha-hydroxy ester derivative | DOW GLOBAL TECHNOLOGIES INC. | 2003-03-18 | — | — | US | disclosed |
| US-20020045707-A1 | Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom | DOW GLOBAL TECHNOLOGIES INC. | 2002-04-18 | — | — | US | disclosed |