Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910551 | 0.75 | CA12 (0.62) | CA12CA1CA2CA9LMNA | |
| SCHEMBL2501561 | 0.74 | MGLL (0.47) | LMNAMAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL12044793 | 0.71 | CA12 (0.50) | CA12CA1CA2CA9LMNA | |
| SCHEMBL12044861 | 0.69 | LMNA (1.00) | LMNAHPGDGRM4MAPTNPC1 | |
| SCHEMBL18770800 | 0.66 | MGLL (0.55) | CA12CA1CA2CA9LMNA | |
| SCHEMBL29879853 | 0.66 | MGLL (0.55) | CA12CA1CA2CA9LMNA | |
| SCHEMBL32667840 | 0.65 | MAPT (0.65) | CA12CA1CA2CA9LMNA | |
| SCHEMBL10381482 | 0.65 | CA4 (0.50) | CA12CA1CA2CA9LMNA | |
| SCHEMBL2550387 | 0.64 | NR1H3 (0.81) | MAPTMGLLNPC1RAB9APOLB | |
| SCHEMBL2115832 | 0.64 | F10 (0.59) | LMNAHPGDMAPTHTTMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038248-A1 | Chemotherapeutic agents | STARPHARMA PTY LTD (AU) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038248-A1 | Chemotherapeutic agents | MKI67, PCNA, MCL1 | CA12 647/4885CA1 1339/4885CA2 1243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.