Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.68 |
| ▸ | DRD2 | P14416 | 5/20 | 0.57 |
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | DRD3 | P35462 | 4/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 3/20 | 0.51 |
| ▸ | DRD5 | P21918 | 2/20 | 0.51 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349852 | 1.00 | DRD4 (0.76) | DRD4KDM4EALDH1A1TSHRHTT | |
| SCHEMBL6349849 | 1.00 | DRD4 (0.76) | DRD4KDM4EALDH1A1TSHRHTT | |
| SCHEMBL6357057 | 0.86 | DRD4 (1.00) | DRD4KDM4EALDH1A1SMN1; SMN2TMEM97 | |
| SCHEMBL6357062 | 0.86 | DRD4 (1.00) | DRD4KDM4EALDH1A1SMN1; SMN2TMEM97 | |
| SCHEMBL6357540 | 0.86 | DRD4 (1.00) | DRD4KDM4EALDH1A1SMN1; SMN2TMEM97 | |
| SCHEMBL6350328 | 0.81 | KDM4E (1.00) | DRD4KDM4EALDH1A1TSHRHTT | |
| SCHEMBL6349951 | 0.75 | DRD4 (1.00) | DRD4TMEM97SIGMAR1DRD2HTR1A | |
| SCHEMBL6352815 | 0.75 | DRD4 (1.00) | DRD4TMEM97SIGMAR1DRD2HTR1A | |
| SCHEMBL6349954 | 0.75 | DRD4 (1.00) | DRD4TMEM97SIGMAR1DRD2HTR1A | |
| SCHEMBL6349808 | 0.74 | DRD4 (0.87) | DRD4SMN1; SMN2TMEM97SIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2005-08-11 | — | — | US | claimed |
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | CYP19A1, SHBG, CYP17A1 | DRD4 1272/4885KDM4E 1593/4885ALDH1A1 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.