Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | HTR1A | P08908 | 5/20 | 0.73 |
| ▸ | DRD2 | P14416 | 4/20 | 0.73 |
| ▸ | HTR2A | P28223 | 4/20 | 0.73 |
| ▸ | DRD3 | P35462 | 4/20 | 0.73 |
| ▸ | DRD4 | P21917 | 2/20 | 0.73 |
| ▸ | HTR2C | P28335 | 2/20 | 0.73 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.73 |
| ▸ | HRH1 | P35367 | 1/20 | 0.73 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6353873 | 0.85 | DRD4 (0.74) | KDM4EALDH1A1TSHRSMN1; SMN2HTT | |
| SCHEMBL6349849 | 0.81 | DRD4 (0.76) | KDM4EALDH1A1TSHRSMN1; SMN2HTT | |
| SCHEMBL6349852 | 0.81 | DRD4 (0.76) | KDM4EALDH1A1TSHRSMN1; SMN2HTT | |
| SCHEMBL6358798 | 0.81 | DRD4 (0.76) | KDM4EALDH1A1TSHRSMN1; SMN2HTT | |
| SCHEMBL9871356 | 0.77 | ALDH1A1 (0.61) | KDM4EALDH1A1TSHRSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL9871634 | 0.76 | HTR2A (0.63) | KDM4EALDH1A1TSHRSMN1; SMN2HTT | |
| SCHEMBL10368830 | 0.76 | ATM (0.61) | KDM4EALDH1A1TSHRSMN1; SMN2HTT | |
| SCHEMBL9660142 | 0.76 | TSHR (0.68) | KDM4EALDH1A1TSHRSMN1; SMN2HTT | |
| SCHEMBL11123253 | 0.76 | ALDH1A1 (0.61) | KDM4EALDH1A1TSHRSMN1; SMN2HTT | |
| SCHEMBL7356339 | 0.76 | ALDH1A1 (0.66) | KDM4EALDH1A1TSHRSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | CYP19A1, SHBG, CYP17A1 | KDM4E 1593/4885ALDH1A1 199/4885TSHR 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.