Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18360692 | 0.78 | CYP2A13 (0.56) | CYP2A13ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL918064 | 0.77 | CYP2A13 (0.68) | CYP2A13ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL6356329 | 0.73 | DRD4 (0.46) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL18360638 | 0.72 | KDM4E (0.57) | CYP2A13ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL6946335 | 0.72 | CYP2A13 (0.64) | CYP2A13ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL8113067 | 0.72 | CYP2A13 (0.64) | CYP2A13ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL10212862 | 0.71 | ALDH1A1 (0.61) | CYP2A13ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL4107051 | 0.71 | CYP2A13 (1.00) | CYP2A13ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL209940 | 0.71 | CYP2A13 (0.68) | CYP2A13ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL3115573 | 0.71 | FUCA1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234090-A1 | Modulators of chemokine receptor activity | PFIZER INC | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234090-A1 | Modulators of chemokine receptor activity | CCR3, CCR2, CCR1 | CYP2A13 1813/4885ALDH1A1 1982/4885LMNA 3682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.