Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6561314 | 0.98 | CYP11B2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL27803362 | 0.77 | CYP11B2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL28809694 | 0.75 | CYP11B2 (0.33) | — | |
| Fluoride Ion SCHEMBL27543397 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL27503699 | 0.72 | — | — | |
| Iodide SCHEMBL27933176 | 0.71 | — | — | |
| Fluoride Ion SCHEMBL27932859 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL1888191 | 0.71 | CYP11B2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL27948698 | 0.71 | CYP11B2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6562630 | 0.71 | CYP11B2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020437-A1 | Microparticulate material | MERCK PATENT GMBH (DE) | 2005-01-27 | — | — | US | disclosed |
| US-6683016-B1 | SLURRYING METALLOCENE AND ACTIVATOR, APPLYING SONIC WAVES OR VIBRATION WAVES, WASHING WITH HYDROCARBON SOLVENT, DRYING; EVEN PENETRATION INTO PORE SPACE OF SUPPORT | DAELIM INDUSTRIAL CO., LTD. (KR) | 2004-01-27 | — | — | US | disclosed |
| US-20040014917-A1 | Catalyst support, production and use thereof in the polymerization of olefins | MERCK PATENT GMBH (DE) | 2004-01-22 | — | — | US | disclosed |
| EP-1042375-B1 | SUPPORTED METALLOCENE CATALYST, ITS PREPARATION METHOD AND OLEFIN POLYMERIZATION THEREWITH | DAELIM IND CO LTD (KR) | 2004-01-02 | — | — | EP | disclosed |
| EP-1042375-A1 | SUPPORTED METALLOCENE CATALYST, ITS PREPARATION METHOD AND OLEFIN POLYMERIZATION THEREWITH | DAELIM INDUSTRIAL CO., LTD. (KR) | 2000-10-11 | — | — | EP | disclosed |
| WO-2000023483-A1 | SUPPORTED METALLOCENE CATALYST, ITS PREPARATION METHOD AND OLEFIN POLYMERIZATION THEREWITH | DAELIM INDUSTRIAL CO., LTD. (KR) | 2000-04-27 | — | — | WO | disclosed |