Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 4/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6350436 | 0.86 | MEN1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL11465302 | 0.86 | LMNA (0.59) | ALDH1A1LMNAPRKCAMAPTMAPK1 | |
| SCHEMBL11455752 | 0.86 | LMNA (0.59) | ALDH1A1LMNAPRKCAMAPTMAPK1 | |
| SCHEMBL11457947 | 0.86 | LMNA (0.59) | ALDH1A1LMNAPRKCAMAPTMAPK1 | |
| SCHEMBL11474946 | 0.86 | LMNA (0.59) | ALDH1A1LMNAPRKCAMAPTMAPK1 | |
| SCHEMBL11457565 | 0.86 | LMNA (0.59) | ALDH1A1LMNAPRKCAMAPTMAPK1 | |
| SCHEMBL11455540 | 0.86 | LMNA (0.59) | ALDH1A1LMNAPRKCAMAPTMAPK1 | |
| SCHEMBL11468104 | 0.79 | PRKCA (0.52) | ALDH1A1LMNAPRKCAMAPTFAAH | |
| SCHEMBL1903350 | 0.76 | — | — | |
| SCHEMBL941154 | 0.74 | LMNA (0.43) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050165201-A1 | Epoxidizing an alpha-halohydrin intermediate from a halide substitution-deesterification of an alpha -hydroxy ester derivative obtained by the coupling reaction of a phenol and a glycidyl ester | BORIACK CLINTON J (US) | 2005-07-28 | — | — | US | disclosed |
| US-20030149219-A1 | Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom | BORIACK CLINTON J (US) | 2003-08-07 | — | — | US | disclosed |
| US-6534621-B2 | Epoxidizing an alpha-halohydrin intermediate produced from an in situ halide substitution-deesterification of an alpha-hydroxy ester derivative | DOW GLOBAL TECHNOLOGIES INC. | 2003-03-18 | — | — | US | disclosed |
| EP-1290058-A2 | PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-03-12 | — | — | EP | disclosed |
| US-20020045707-A1 | Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom | DOW GLOBAL TECHNOLOGIES INC. | 2002-04-18 | — | — | US | disclosed |
| WO-2001088013-A2 | PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM | DOW GLOBAL TECHNOLOGIES INC (US) | 2001-11-22 | — | — | WO | disclosed |