Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 11/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753064 | 1.00 | KDM4E (0.53) | KDM4EGLAMYCNR4A1SORT1 | |
| Hydrochloric Acid SCHEMBL7676438 | 0.98 | KDM4E (0.52) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL5761315 | 0.83 | ALDH1A1 (0.53) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL29420640 | 0.83 | MAPT (0.49) | MYCNR4A1SORT1FLT1FLT4 | |
| SCHEMBL17332 | 0.83 | KDM4E (0.59) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL29571243 | 0.83 | KDM4E (0.59) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL3173571 | 0.83 | FLT1 (0.46) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL117133 | 0.83 | MAPT (0.49) | MYCNR4A1SORT1FLT1FLT4 | |
| SCHEMBL7561415 | 0.81 | HPGD (0.47) | KDM4EGLAMYCNR4A1 | |
| SCHEMBL428805 | 0.81 | DGAT1 (0.60) | KDM4EGLARXFP1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2884 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907236-B | Aldoxime compound and preparation method and application thereof | 四川青木制药有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-117186022-A | Method for efficiently synthesizing fluororalrana | 内蒙古联邦动保药品有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-116987042-A | Synthesis method of fluororalrana | 杭州丰禧生物科技有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | claimed |
| CN-115160134-B | Preparation method of 4-bromo-2-methyl benzoate | 无锡科华生物科技有限公司 | 2023-10-10 | — | — | CN | claimed |
| CN-115304472-A | Synthetic method of intermediate 4-bromo-2-methylbenzoic acid of Freund Lei Lana | 重庆医药高等专科学校 | 2022-11-08 | — | — | CN | claimed |
| CN-217646394-U | A reation kettle for 4-bromo-2-methyl benzoate is synthetic | 上海率典医药科技有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-115160134-A | Preparation method of 4-bromo-2-methyl benzoate | 无锡科华生物科技有限公司 | 2022-10-11 | — | — | CN | claimed |
| CN-115141097-A | Intermediate 4-bromine of Freund Lei Lana-2-methylbenzoic acid's production line system | 重庆医药高等专科学校 | 2022-10-04 | — | — | CN | claimed |
| CN-114907236-A | Aldoxime compound and preparation method and application thereof | 四川青木制药有限公司 | 2022-08-16 | — | — | CN | claimed |
| US-20110207901-A1 | INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II | BASF CATALYSTS LLC (US) | 2011-08-25 | — | — | US | claimed |
| WO-2011084691-A2 | NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS | BASF CORPORATION (US) | 2011-07-14 | — | — | WO | claimed |
| US-20110152481-A1 | Internal and external donor compounds for olefin polymerization catalysts | BASF CATALYSTS LLC (US) | 2011-06-23 | — | — | US | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-6586599-B1 | Formating carbon-carbon bonds between carbocyclic halogen and organosilicon compounds in the presence of coordination catalysts, nitrogen compounds and bases; efficiency; catalysis | UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION | 2003-07-01 | — | — | US | claimed |
| US-6369265-B1 | HETEROCOUPLING REACTION, MIXING IN A LIQUID AN ARYL HALIDE, BONDING TO AROMATIC RINGS, GRIGNARD REACTION, METAL COMPOUND AND HETEROCYCLIC CARBENE | UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION | 2002-04-09 | — | — | US | claimed |
| WO-2001066248-A2 | C-C AND C-N COUPLING CATALYST COMPRISING TRANSITION METAL AND CARBENE | UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION (US) | 2001-09-13 | — | — | WO | claimed |
| EP-0069810-B1 | NOVEL DIBENZOXEPINS, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THE USE OF DIBENZOXEPINS IN THE TREATMENT OF ALLERGIC CONDITIONS | MERCK & CO. INC. (US) | 1986-12-03 | — | — | EP | claimed |
| EP-0081384-B1 | PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC CARBOXYLATED COMPOUNDS | Montedison S.p.A. (IT) | 1986-04-02 | — | — | EP | claimed |
| EP-0069810-A1 | Novel dibenzoxepins, their preparation, compositions containing them and the use of dibenzoxepins in the treatment of allergic conditions | MERCK & CO. INC. (US) | 1983-01-19 | — | — | EP | claimed |