SCHEMBL17332

SCHEMBL17332

Cc1ccc(Br)cc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.59
GLA P06280 1/20 0.59
MYC P01106 1/20 0.58
NR4A1 P22736 1/20 0.58
SORT1 Q99523 9/20 0.53
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
METAP2 P50579 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47
GPR35 Q9HC97 1/20 0.47
CES2 O00748 1/20 0.47
GALR3 O60755 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
CASP1 P29466 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29571243 1.00 KDM4E (0.59) KDM4EGLAMYCNR4A1SORT1
SCHEMBL16050286 0.88 ALDH1A1 (0.50) KDM4EGLAMYCNR4A1SORT1
SCHEMBL27298440 0.83 ALDH1A1 (0.57) KDM4EGLAMYCNR4A1SORT1
SCHEMBL30753064 0.83 KDM4E (0.53) KDM4EGLAMYCNR4A1SORT1
SCHEMBL6360 0.83 KDM4E (0.53) KDM4EGLAMYCNR4A1SORT1
SCHEMBL30976481 0.83 MAOA (0.50) KDM4EGLAMYCNR4A1SORT1
SCHEMBL9353897 0.83 MAOA (0.50) KDM4EGLAMYCNR4A1SORT1
SCHEMBL31200433 0.81 DGAT1 (0.55) KDM4EGLAMYCNR4A1SORT1
SCHEMBL18431 0.81 ALDH1A1 (0.46) KDM4EGLAMYCNR4A1SORT1
SCHEMBL1788262 0.81 DGAT1 (0.55) KDM4EGLAMYCNR4A1SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 868 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930421-A Synthesis method of 5-bromo-2-methylbenzoic acid 浙江天宇药业股份有限公司 2025-05-06 CN claimed
CN-118580180-A Intermediate of EZH2 inhibitor, and preparation method and application thereof 上海市第七人民医院 2024-09-03 CN claimed
CN-117105779-A Preparation method of 5-bromo-2-formylbenzoic acid methyl ester 河南师范大学 2023-11-24 CN claimed
CN-113527313-B Preparation method and application of water-soluble supermolecule organic cage-shaped compound for detecting pyridinium substances in water 浙江浙能技术研究院有限公司 2022-07-12 CN claimed
US-20220024950-A1 METHOD FOR PREPARING BORIC ACID ESTER BASED ON LITHIUM COMPOUND SOOCHOW UNIVERSITY (CN) 2022-01-27 US claimed
CN-113527313-A Preparation method and application of water-soluble supermolecule organic cage-shaped compound for detecting pyridinium substances in water 浙江浙能技术研究院有限公司 2021-10-22 CN claimed
CN-113149828-A Preparation method of 5-bromo-2-methylbenzoic acid 山东寿光增瑞化工有限公司 2021-07-23 CN claimed
CN-109503641-B Method for preparing borate ester based on anilino lithium compound 苏州大学 2021-01-01 CN claimed
CN-109369696-B Method for preparing alcohol compound by using anilino lithium compound as catalyst 苏州大学 2021-01-01 CN claimed
CN-109438493-B Method for preparing borate based on n-butyl lithium 苏州大学 2020-09-08 CN claimed
WO-2020118922-A1 METHOD FOR PREPARING BORIC ACID ESTER BASED ON LITHIUM COMPOUND 苏州大学 2020-06-18 WO claimed
WO-2020113835-A1 METHOD FOR PREPARING BORIC ACID ESTER USING UNCATALYZED HYDROBORATION OF CARBOXYLIC ACID 苏州大学 2020-06-11 WO claimed
CN-104892566-A Preparation method of 2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene SHANGHAI INST TECHNOLOGY 2015-09-09 CN claimed
EP-0069810-B1 NOVEL DIBENZOXEPINS, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THE USE OF DIBENZOXEPINS IN THE TREATMENT OF ALLERGIC CONDITIONS MERCK & CO. INC. (US) 1986-12-03 EP claimed
EP-0069810-A1 Novel dibenzoxepins, their preparation, compositions containing them and the use of dibenzoxepins in the treatment of allergic conditions MERCK & CO. INC. (US) 1983-01-19 EP claimed
US-12612426-B2 Aryl glucoside derivative SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2026-04-28 US disclosed
US-12612427-B2 Aryl glucoside derivative, preparation method therefor and application thereof SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2026-04-28 US disclosed
EP-0069810-A1 Novel dibenzoxepins, their preparation, compositions containing them and the use of dibenzoxepins in the treatment of allergic conditions MERCK & CO. INC. (US) 1983-01-19 EP disclosed
US-4282365-A Dibenz[b,e]oxepin compounds MERCK & CO., INC. (US) 1981-08-04 US disclosed
US-3953595-A Substituted benzoic acid hypolipemic agents PFIZER INC. (US) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612426-B2 Aryl glucoside derivative SLC5A1, SLC5A2, GPR119 KDM4E 3750/4885GLA 1372/4885MYC 1419/4885
US-12612427-B2 Aryl glucoside derivative, preparation method therefor and application thereof SLC5A1, SLC10A1, SLC5A2 KDM4E 4429/4885GLA 1296/4885MYC 2201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.