Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.65 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358531 | 1.00 | DPP4 (0.65) | DPP4DPP7KCNH2 | |
| SCHEMBL14656014 | 0.92 | DPP4 (0.73) | DPP4DPP7KCNH2 | |
| SCHEMBL14750994 | 0.89 | DPP4 (0.63) | DPP4DPP7KCNH2 | |
| SCHEMBL15203460 | 0.86 | DPP4 (0.69) | DPP4DPP7KCNH2 | |
| SCHEMBL5477707 | 0.86 | DPP4 (0.69) | DPP4DPP7KCNH2 | |
| SCHEMBL23655651 | 0.85 | DPP4 (0.67) | DPP4DPP7KCNH2 | |
| SCHEMBL14392401 | 0.85 | DPP4 (0.67) | DPP4DPP7KCNH2 | |
| SCHEMBL6820738 | 0.85 | DPP4 (0.67) | DPP4DPP7KCNH2 | |
| SCHEMBL15203483 | 0.85 | DPP4 (0.67) | DPP4DPP7KCNH2 | |
| SCHEMBL14392636 | 0.85 | DPP4 (0.67) | DPP4DPP7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100334-A1 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2005-10-27 | — | — | WO | disclosed |
| US-20050234065-A1 | Dipeptidyl peptidase-IV inhibitors | PFIZER INC | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234065-A1 | Dipeptidyl peptidase-IV inhibitors | ALPI, DPP4, SI | DPP4 2/4885DPP7 11/4885KCNH2 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.