Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 14/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 14/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.59 |
| ▸ | ATP4A | P20648 | 4/20 | 0.40 |
| ▸ | ATP4B | P51164 | 4/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352082 | 0.86 | CYP3A4 (0.73) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL6354394 | 0.83 | CYP3A4 (0.57) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL6356025 | 0.82 | CYP3A4 (0.59) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL2193750 | 0.79 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL6354554 | 0.78 | CYP3A4 (0.62) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL6352406 | 0.78 | CYP3A4 (0.62) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL6360648 | 0.77 | CYP3A4 (0.79) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL7500392 | 0.77 | CYP3A4 (0.88) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL6361010 | 0.76 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL6360301 | 0.75 | CYP3A4 (0.56) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050154007-A1 | New compounds | AMIN KOSRAT (SE) | 2005-07-14 | — | — | US | disclosed |
| EP-1411056-A2 | Imidazo[1,2-a]pyridine compounds that inhibit gastric acid secretion, pharmaceutical compositions thereof, and processes for their preparation | AstraZeneca AB (SE) | 2004-04-21 | — | — | EP | disclosed |
| US-6579884-B1 | Compounds | ASTRAZENECA AB (SE) | 2003-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154007-A1 | New compounds | SLC10A2, GIPR, FABP6 | CYP3A4 2475/4885CYP2C9 3139/4885CYP2D6 2771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.