Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6361145 | 0.75 | MAOA (0.34) | MAOAMAOBKDM1ASLC6A4SLC6A3 | |
| SCHEMBL12696323 | 0.70 | MAOB (0.42) | MAOAMAOBKDM1ASLC6A4SLC6A3 | |
| SCHEMBL5375847 | 0.68 | MAOA (0.34) | MAOAMAOBKDM1ASLC6A4SLC6A3 | |
| SCHEMBL28453720 | 0.65 | SLC6A3 (0.39) | SLC6A4SLC6A3 | |
| SCHEMBL5866578 | 0.65 | SLC6A4 (0.37) | MAOAMAOBKDM1ASLC6A4SLC6A3 | |
| SCHEMBL668905 | 0.62 | SLC6A4 (0.47) | MAOAMAOBKDM1ASLC6A4SLC6A3 | |
| SCHEMBL11170584 | 0.62 | — | — | |
| SCHEMBL6352243 | 0.62 | SLC6A4 (0.33) | MAOAMAOBKDM1ASLC6A4SLC6A3 | |
| SCHEMBL31097812 | 0.62 | MAOA (0.31) | MAOAMAOB | |
| SCHEMBL8478708 | 0.59 | SLC6A4 (0.53) | SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936607-B2 | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety | H. LUNOBECK A/S (DK) | 2005-08-30 | — | — | US | disclosed |