Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18376119 | 0.79 | AAK1 (0.39) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL637918 | 0.78 | KMT2A (0.67) | KMT2AMEN1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL5211782 | 0.78 | KMT2A (0.82) | KMT2AMEN1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL29649689 | 0.78 | KMT2A (0.82) | KMT2AMEN1MAPK1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL636048 | 0.77 | KMT2A (0.66) | KMT2AMEN1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL2891610 | 0.77 | KMT2A (0.77) | KMT2AMEN1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL4380392 | 0.76 | KMT2A (0.67) | KMT2AMEN1MAPK1CYP1A2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL6606007 | 0.76 | KMT2A (0.67) | KMT2AMEN1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL5200890 | 0.75 | GLA (0.47) | KMT2AMEN1MAPK1HPGDGLA | |
| SCHEMBL784479 | 0.74 | ALDH1A1 (0.52) | KMT2AMEN1MAPK1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565441-B1 | Process for the preparation of 2-aminomethylpyridine derivatives | BAYER CROPSCIENCE SA (FR) | 2012-02-22 | — | — | EP | disclosed |
| US-7232911-B2 | Process for the preparation of 2-aminomethylpyridine derivative | BAYER CROPSCIENCE S.A. (FR) | 2007-06-19 | — | — | US | disclosed |
| US-20060100441-A1 | Process for the preparation of 2-aminomethylpyridine derivative | BAYER CROPSCIENCE LIMITED (GB) | 2006-05-11 | — | — | US | disclosed |
| EP-1565441-A2 | PROCESS FOR THE PREPARATION OF 2-AMINOMETHYLPYRIDINE DERIVATIVE | Bayer CropScience S.A. (FR) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004065359-A2 | PROCESS FOR THE PREPARATION OF 2-AMINOMETHYLPYRIDINE DERIVATIVE | BAYER CROPSCIENCE S.A. (FR) | 2004-08-05 | — | — | WO | disclosed |
| EP-1422220-A1 | Process for the preparation of 2-aminomethylpyridine derivative | Bayer CropScience SA (FR) | 2004-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100441-A1 | Process for the preparation of 2-aminomethylpyridine derivative | AZI2, CYP2C9, ABL2 | KMT2A 302/4885MEN1 2143/4885MAPK1 974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.