Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200890 | 0.78 | GLA (0.47) | ALDH1A1PKMGAALMNAGLA | |
| SCHEMBL4961217 | 0.75 | L3MBTL1 (0.81) | ALDH1A1PKMGAALMNAMAPT | |
| SCHEMBL636057 | 0.74 | KMT2A (0.56) | ALDH1A1GAALMNAL3MBTL1GLA | |
| SCHEMBL6157186 | 0.71 | ALDH1A1 (0.47) | ALDH1A1PKMGAALMNAMAPT | |
| SCHEMBL7586393 | 0.71 | ALDH1A1 (0.47) | ALDH1A1PKMGAALMNAMAPT | |
| SCHEMBL4452273 | 0.71 | ALDH1A1 (0.56) | ALDH1A1PKMGAALMNAMAPT | |
| SCHEMBL14921128 | 0.70 | L3MBTL1 (0.60) | ALDH1A1PKMGAALMNAMAPT | |
| SCHEMBL18292261 | 0.70 | L3MBTL1 (0.64) | ALDH1A1PKMGAALMNAMAPT | |
| SCHEMBL5202284 | 0.69 | GLA (0.53) | ALDH1A1GAALMNAMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL784570 | 0.69 | L3MBTL1 (0.59) | ALDH1A1PKMGAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694648-B1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | BAYER SAS (FR) | 2015-07-29 | — | — | EP | disclosed |
| EP-1694649-B1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2014-01-22 | — | — | EP | disclosed |
| US-8318777-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER SAS (FR) | 2012-11-27 | — | — | US | disclosed |
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2012-03-22 | — | — | US | disclosed |
| US-8071627-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER SAS (FR) | 2011-12-06 | — | — | US | disclosed |
| EP-1204642-B1 | FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-10-13 | — | — | EP | disclosed |
| US-7560567-B2 | 2-pyridinylethylbenzamide derivatives | BAYER CROPSCIENCE S.A. (FR) | 2009-07-14 | — | — | US | disclosed |
| US-20090088456-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as Fugicides | BAYER CROPSCIENCE S.A. | 2009-04-02 | — | — | US | disclosed |
| US-20070117845-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER CROPSCIENCE S.A. (FR) | 2007-05-24 | — | — | US | disclosed |
| US-20070099965-A1 | 2-Pyridinylethylbenzamide derivatives | BAYER SAS (FR) | 2007-05-03 | — | — | US | disclosed |
| EP-1694648-A1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | Bayer CropScience S.A. (FR) | 2006-08-30 | — | — | EP | disclosed |
| EP-1694649-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | Bayer CropScience S.A. (FR) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005058828-A1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE S.A. (FR) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058833-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2005-06-30 | — | — | WO | disclosed |
| EP-1548007-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as fungicides | Bayer CropScience S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| EP-1204322-B1 | FUNGICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2005-02-09 | — | — | EP | disclosed |
| US-6630495-B1 | Compound containing 2-pyridyl or its N-oxide | BAYER CROPSCIENCE GMBH (DE) | 2003-10-07 | — | — | US | disclosed |
| EP-1204322-A1 | FUNGICIDES | Aventis CropScience GmbH (DE) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001011966-A1 | FUNGICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2001-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088456-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as Fugicides | PFAS, CYP4F2, FPGS | ALDH1A1 1119/4885PKM 842/4885GAA 83/4885 |
| US-20070117845-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as fungicides | CYP1A2, PNPO, PFAS | ALDH1A1 1103/4885PKM 503/4885GAA 114/4885 |
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A2, CYP51A1, CYP3A5 | ALDH1A1 831/4885PKM 573/4885GAA 230/4885 |
| US-20070099965-A1 | 2-Pyridinylethylbenzamide derivatives | CYP1A2, CYP4B1, CYP4F2 | ALDH1A1 772/4885PKM 258/4885GAA 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.