SCHEMBL6360577

SCHEMBL6360577

C=C(C(N)=O)C1CCC(O)CC1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.34
TDP1 Q9NUW8 1/20 0.32
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL730807 0.90 TDP1 (0.38) TDP1NOS2
SCHEMBL543402 0.90
Propane SCHEMBL28407353 0.81 SMN1; SMN2 (0.38) TDP1NOS2
SCHEMBL20272049 0.81 TDP1 (0.32) TDP1NOS2
SCHEMBL532571 0.80 CES2 (0.43) TDP1NOS2
SCHEMBL4743865 0.80
SCHEMBL4079495 0.78 CES2 (0.48) TDP1NOS2
SCHEMBL163416 0.78 CES2 (0.48) TDP1NOS2
SCHEMBL3114031 0.78 CES2 (0.48) TDP1NOS2
SCHEMBL2200499 0.78 EPHX2 (0.36) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1591462-A2 Temperature-responsive polymer compound and process for producing the same Amersham Biosciences KK (JP) 2005-11-02 EP disclosed
US-6956077-B1 Temperature-responsive polymer compound and process for producing the same AMERSHAM BIOSCIENCES KK (JP) 2005-10-18 US disclosed
US-20050224415-A1 Temperature-responsive polymer compound and process for producing the same AMERSHAM BIOSCIENCES KK 2005-10-13 US disclosed
EP-1153049-A1 TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME Amersham Pharmacia Biotech K.K. (JP) 2001-11-14 EP disclosed
WO-2000044800-A1 TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME AMERSHAM PHARMACIA BIOTECH K.K. (JP) 2000-08-03 WO disclosed