SCHEMBL730807

SCHEMBL730807

C=C(C(N)=O)C1CCC(C(=C)C(N)=O)CC1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
NOS2 P35228 1/20 0.36
PLG P00747 1/20 0.32
PLAT P00750 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 2/20 0.30
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
ATM Q13315 1/20 0.30
LDHA P00338 1/20 0.30
LDHB P07195 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL543402 1.00
Propane SCHEMBL28407353 0.90 SMN1; SMN2 (0.38) TDP1NOS2PLGPLATLMNA
SCHEMBL20272049 0.90 TDP1 (0.32) TDP1NOS2
SCHEMBL6360577 0.90 EPHX2 (0.34) TDP1NOS2
SCHEMBL532571 0.89 CES2 (0.43) TDP1NOS2KMT2AKDM4EMAPT
SCHEMBL4743865 0.89
SCHEMBL3114031 0.87 CES2 (0.48) TDP1NOS2KMT2AKDM4EMAPT
SCHEMBL4079495 0.87 CES2 (0.48) TDP1NOS2KMT2AKDM4EMAPT
SCHEMBL163416 0.87 CES2 (0.48) TDP1NOS2KMT2AKDM4EMAPT
SCHEMBL30679180 0.86 PLG (0.39) TDP1PLGPLATLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3063210-A2 METHOD OF THIOPHENOL REMOVAL FROM POLY(ARYLENE SULFIDE) POLYMER COMPOSITIONS SOLVAY SA (BE) 2016-09-07 EP disclosed
US-9388282-B2 Method of thiophenol removal from poly(arylene sulfide) polymer compositions SOLVAY SPECIALTY POLYMERS USA, LLC. (US) 2016-07-12 US disclosed
WO-2015065906-A2 METHOD OF THIOPHENOL REMOVAL FROM POLY(ARYLENE SULFIDE) POLYMER COMPOSITIONS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-05-07 WO disclosed
US-20150119550-A1 Method of Thiophenol Removal from Poly(Arylene Sulfide) Polymer Compositions CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-04-30 US disclosed
US-8889802-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2014-11-18 US disclosed
US-20120130040-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2012-05-24 US disclosed
EP-2448990-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME Polymeright Inc. (US) 2012-05-09 EP disclosed
US-8138278-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2012-03-20 US disclosed
US-20110152492-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2011-06-23 US disclosed
WO-2011008480-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME POLYMERIGHT, INC. (US) 2011-01-20 WO disclosed
US-7585932-B2 Polymer compositions and processes for making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-09-08 US disclosed
EP-1940917-A2 POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2008-07-09 EP disclosed
US-20070055033-A1 POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2007-03-08 US disclosed
WO-2007021960-A2 POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-02-22 WO disclosed
US-6777494-B1 POLYTHIOURETHANE AND POLYTHIOETHER POLYMERS FORMED MAY BE USED ALONE OR MIXED FOR OPTICAL PURPOSES SUCH AS THE MANUFACTURE OF OPHTHALMIC LENSES OPTIMA INC. 2004-08-17 US disclosed
US-6008296-A CURABLE MONOMER COMPOSITION COMPRISING A POLYISOCYANATE OR POLYTHIOISOCYANATE, POLYTHIOL, AND POLYENE OF GIVEN FORMULA; NO PHASE SEPERATION, SINGLE GLASS TRANSITION TEMPERATURE, IMPACT RESISTANCE AND HIGH REFRACTIVE INDEX FOR EYEGLASSES OPTIMA, INC. (US) 1999-12-28 US disclosed
EP-0473346-A2 Rewritable organic recording medium, process for the production thereof, and method of recording and erasing TEIJIN LIMITED (JP) 1992-03-04 EP disclosed
US-5047576-A Polymerizable vinyl compound having polythioether skeleton SHOWA DENKO KABUSHIKI KAISHA (JP) 1991-09-10 US disclosed
EP-0284374-A2 Polymerizable vinyl compound having polythioether skeleton, process for preparation thereof and optical element made therefrom SHOWA DENKO KABUSHIKI KAISHA (JP) 1988-09-28 EP disclosed