Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 16/20 | 0.73 |
| ▸ | DHFR | P00374 | 2/20 | 0.63 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359947 | 0.84 | GHSR (1.00) | GHSRDHFRNCOA1NCOA3 | |
| SCHEMBL6364083 | 0.84 | GHSR (0.70) | GHSRDHFRNCOA1NCOA3 | |
| SCHEMBL6360829 | 0.80 | GHSR (0.80) | GHSRDHFRNCOA1NCOA3 | |
| SCHEMBL6360512 | 0.78 | GHSR (1.00) | GHSRDHFR | |
| SCHEMBL6364061 | 0.76 | GHSR (1.00) | GHSRDHFR | |
| SCHEMBL6358641 | 0.75 | GHSR (1.00) | GHSR | |
| SCHEMBL6360247 | 0.75 | GHSR (1.00) | GHSR | |
| SCHEMBL6358993 | 0.75 | GHSR (0.82) | GHSR | |
| SCHEMBL6364388 | 0.74 | GHSR (0.80) | GHSR | |
| SCHEMBL6361334 | 0.74 | GHSR (1.00) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | KOSOGOF CHRISTI (US) | 2005-08-04 | — | — | US | claimed |
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | KOSOGOF CHRISTI (US) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | GHSR, GIPR, GPR119 | GHSR 1/4885DHFR 465/4885NCOA1 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.