Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.69 |
| ▸ | DRD4 | P21917 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349970 | 0.84 | DRD4 (0.74) | HTR1ADRD4 | |
| SCHEMBL6349965 | 0.84 | DRD4 (0.74) | HTR1ADRD4 | |
| SCHEMBL6350053 | 0.82 | DRD4 (0.73) | HTR1ADRD4 | |
| SCHEMBL6360134 | 0.82 | HTR1A (1.00) | HTR1ADRD4ALDH1A1KMT2AGFER | |
| SCHEMBL6359307 | 0.80 | DRD4 (1.00) | DRD4 | |
| SCHEMBL6359310 | 0.80 | DRD4 (1.00) | DRD4 | |
| SCHEMBL6351416 | 0.80 | HTR1A (1.00) | HTR1ADRD4 | |
| SCHEMBL16026463 | 0.78 | KMT2A (0.83) | HTR1AALDH1A1KMT2AGFERMAPT | |
| Hydrochloric Acid SCHEMBL7934846 | 0.77 | KMT2A (0.83) | HTR1AALDH1A1KMT2AGFERMAPT | |
| SCHEMBL4402731 | 0.76 | DRD4 (0.54) | DRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | CYP19A1, SHBG, CYP17A1 | HTR1A 871/4885DRD4 1272/4885ALDH1A1 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.