Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.63 |
| ▸ | FPR1 | P21462 | 1/20 | 0.57 |
| ▸ | FPR2 | P25090 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683366 | 0.94 | F10 (0.69) | F10FPR1FPR2 | |
| Hydrochloric Acid SCHEMBL6366490 | 0.89 | F10 (0.51) | F10FPR1FPR2 | |
| Hydrochloric Acid SCHEMBL6365725 | 0.88 | F10 (0.54) | F10 | |
| SCHEMBL4682683 | 0.83 | F10 (0.69) | F10FPR1FPR2 | |
| SCHEMBL6362511 | 0.82 | FPR2 (0.69) | F10FPR1FPR2 | |
| SCHEMBL6362632 | 0.81 | F10 (0.46) | F10FPR1FPR2 | |
| SCHEMBL4683935 | 0.80 | F10 (0.63) | F10FPR1FPR2 | |
| SCHEMBL4683472 | 0.79 | F10 (0.52) | F10FPR1FPR2 | |
| Hydrochloric Acid SCHEMBL6361892 | 0.78 | F10 (0.41) | F10FPR1FPR2 | |
| SCHEMBL20555885 | 0.78 | FPR2 (0.77) | F10FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059726-A1 | Pyrrolidine-2-ones as factor xa inhibitors | GLAXO GROUP LIMITED (GB) | 2005-03-17 | — | — | US | disclosed |
| EP-1456172-A1 | PYRROLIDINE-2-ONES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053925-A1 | PYRROLIDINE-2-ONES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059726-A1 | Pyrrolidine-2-ones as factor xa inhibitors | TFPI, F2, SERPINC1 | F10 7/4885FPR1 641/4885FPR2 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.