Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.83 |
| ▸ | HRH1 | P35367 | 5/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873505 | 0.90 | HRH1 (0.90) | KCNH2HRH1KDM4EALDH1A1ACHE | |
| SCHEMBL7442047 | 0.90 | KCNH2 (0.69) | KCNH2HRH1KDM4EALDH1A1ACHE | |
| SCHEMBL3240024 | 0.90 | KCNH2 (0.78) | KCNH2HRH1KDM4EALDH1A1HTT | |
| SCHEMBL9787488 | 0.89 | HRH1 (0.78) | KCNH2HRH1HTTNPSR1 | |
| Hydrochloric Acid SCHEMBL8200558 | 0.89 | KCNH2 (0.67) | KCNH2HRH1KDM4EALDH1A1ACHE | |
| Hydrochloric Acid SCHEMBL11692629 | 0.89 | KCNH2 (0.76) | KCNH2HRH1KDM4EALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL9787500 | 0.87 | HRH1 (0.76) | KCNH2HRH1HTTNPSR1 | |
| SCHEMBL7432282 | 0.87 | KCNH2 (0.66) | KCNH2HRH1KDM4EALDH1A1ACHE | |
| SCHEMBL9873080 | 0.86 | HRH1 (0.67) | KCNH2HRH1ACHECHRM3 | |
| SCHEMBL10735878 | 0.85 | KCNH2 (0.63) | KCNH2HRH1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107257-A1 | Derivatives of (1-benzyl-piperidine-4-yl)-diphenyl-methanol and their use as pesticide | SYNGENTA CROP PROTECTION, INC. | 2005-05-19 | — | — | US | disclosed |
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |
| US-4886794-A | ANTIHISTAMINES, ANTIALLERGENS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-12-12 | — | — | US | disclosed |
| EP-0291244-A1 | Cyclic carbamate derivatives | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1988-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107257-A1 | Derivatives of (1-benzyl-piperidine-4-yl)-diphenyl-methanol and their use as pesticide | DDT, CHRM1, PYM1 | KCNH2 13/4885HRH1 208/4885KDM4E 1688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.