Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.59 |
| ▸ | NPY2R | P49146 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10461604 | 0.94 | HRH1 (0.60) | HRH1KCNH2SIGMAR1CYP2J2NPY2R | |
| SCHEMBL8792635 | 0.89 | HRH1 (0.58) | HRH1KCNH2SIGMAR1CYP2J2NPY2R | |
| SCHEMBL9504518 | 0.86 | SIGMAR1 (0.64) | HRH1KCNH2SIGMAR1CYP2J2NPY2R | |
| SCHEMBL6362147 | 0.86 | KCNH2 (0.83) | HRH1KCNH2ACHECHRM3 | |
| Hydrochloric Acid SCHEMBL9787492 | 0.85 | SIGMAR1 (0.62) | HRH1KCNH2SIGMAR1CYP2J2NPY2R | |
| SCHEMBL7472985 | 0.85 | LMNA (0.56) | HRH1KCNH2CYP2J2NPY2RACHE | |
| SCHEMBL9873505 | 0.85 | HRH1 (0.90) | HRH1KCNH2CYP2J2ACHEBACE1 | |
| SCHEMBL7477007 | 0.85 | KCNH2 (0.62) | HRH1KCNH2NPY2RACHEBACE1 | |
| Hydrochloric Acid SCHEMBL7473216 | 0.84 | KCNH2 (0.60) | HRH1KCNH2NPY2RACHEBACE1 | |
| SCHEMBL7442047 | 0.83 | KCNH2 (0.69) | HRH1KCNH2SIGMAR1ACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |
| US-4886794-A | ANTIHISTAMINES, ANTIALLERGENS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-12-12 | — | — | US | disclosed |
| EP-0291244-A1 | Cyclic carbamate derivatives | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1988-11-17 | — | — | EP | disclosed |