⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10437776 | 0.79 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL11073192 | 0.77 | — | — | |
| SCHEMBL27535613 | 0.76 | ALDH1A1 (0.41) | — | |
| SCHEMBL2643129 | 0.76 | — | — | |
| SCHEMBL9600541 | 0.71 | — | — | |
| SCHEMBL2642803 | 0.71 | — | — | |
| SCHEMBL5685885 | 0.68 | GAA (0.33) | — | |
| SCHEMBL10777149 | 0.68 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL2642609 | 0.68 | PIK3CG (0.53) | — | |
| Hydrochloric Acid SCHEMBL9725667 | 0.68 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050245498-A1 | Sterically-awkward beta-lactamase inhibitors | NORTHWESTERN UNIVERSITY | 2005-11-03 | — | — | US | claimed |
| US-6124297-A | COMBATTING INSECTS OR MITES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-26 | — | — | US | claimed |
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | claimed |
| EP-0302389-B1 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-22 | — | — | EP | claimed |
| EP-0548338-A1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS INTERMEDIATES. | ANTIBIOTICOS SPA (IT) | 1993-06-30 | — | — | EP | claimed |
| WO-1993002085-A1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS INTERMEDIATES | ANTIBIOTICOS S.P.A. (IT) | 1993-02-04 | — | — | WO | claimed |
| US-20050245498-A1 | Sterically-awkward beta-lactamase inhibitors | NORTHWESTERN UNIVERSITY | 2005-11-03 | — | — | US | disclosed |
| WO-2004037163-A2 | STERICALLY-AWKWARD β-LACTAMASE INHIBITORS | NORTHWESTERN UNIVERSITY (US) | 2004-05-06 | — | — | WO | disclosed |
| US-20030236243-A1 | Sterically-awkward beta-lactamase inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-12-25 | — | — | US | disclosed |
| CN-1083432-C | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-04-24 | — | — | CN | disclosed |
| CN-1051547-C | Beta-lactams derivative and its prep. and use | HOFFMANN LA ROCHE (CH) | 2000-04-19 | — | — | CN | disclosed |
| CN-1036649-C | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-12-10 | — | — | CN | disclosed |
| CN-1132752-A | Beta-lactam derivatives, process for their preparation and their use | HOFFMANN LA ROCHE (CH) | 1996-10-09 | — | — | CN | disclosed |
| CN-1091737-A | The method for preparing amine compound or its salt | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-09-07 | — | — | CN | disclosed |
| CN-1021910-C | LANKACIDIN DERIVATIVES AND PRODUCTION THEREOF | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-08-25 | — | — | CN | disclosed |
| CN-1017902-B | PROCESS FOR THE PREPARATION OF NOVEL CEPHALOSPORIN DERIVATIVES | MEIJI PHARMACEUTIAL LTD (JP) | 1992-08-19 | — | — | CN | disclosed |
| CN-1063014-A | Stable composition pesticide | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-07-29 | — | — | CN | disclosed |
| EP-0366189-A2 | Novel antimicrobial lactam-quinolones | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | disclosed |
| CN-1031079-A | Alpha-unsaturated amines, process for their production and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1989-02-15 | — | — | CN | disclosed |
| CN-86108176-A | Lankacidin derivatives and process for producing the same | — | 1987-10-21 | — | — | CN | disclosed |