⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2643129 | 0.76 | — | — | |
| SCHEMBL27736465 | 0.71 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL2642803 | 0.71 | — | — | |
| SCHEMBL6363648 | 0.71 | — | — | |
| SCHEMBL28302363 | 0.71 | — | — | |
| SCHEMBL27851069 | 0.70 | HSD17B10 (0.47) | — | |
| SCHEMBL16095753 | 0.69 | GSTO1 (0.47) | — | |
| SCHEMBL2642609 | 0.69 | PIK3CG (0.53) | — | |
| SCHEMBL10777149 | 0.69 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL10719025 | 0.68 | ALDH1A1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |
| US-4565655-A | Diazabicyclononene antibacterials | ELI LILLY AND COMPANY (US) | 1986-01-21 | — | — | US | disclosed |