Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364356 | 1.00 | KDM1A (0.45) | KDM1APDK2GPR119BCHESCN9A | |
| SCHEMBL6364363 | 1.00 | KDM1A (0.45) | KDM1APDK2GPR119BCHESCN9A | |
| SCHEMBL6364627 | 0.71 | CETP (0.47) | PDK2NOTUM | |
| SCHEMBL30921574 | 0.68 | KDM1A (0.53) | KDM1APDK2GPR119BCHESCN9A | |
| SCHEMBL8876973 | 0.67 | KDM1A (0.44) | KDM1APDK2BCHESCN9ANOTUM | |
| SCHEMBL30630786 | 0.66 | KDM1A (0.45) | KDM1AGPR119BCHESCN9ANOTUM | |
| SCHEMBL30630651 | 0.66 | KDM1A (0.46) | KDM1ABCHESCN9ANOTUMRORC | |
| SCHEMBL30681428 | 0.66 | BCHE (0.46) | KDM1AGPR119BCHESCN9ARORC | |
| SCHEMBL22341799 | 0.65 | KDM1A (0.44) | KDM1AGPR119BCHESCN9ANOTUM | |
| SCHEMBL22355687 | 0.65 | KDM1A (0.44) | KDM1AGPR119BCHESCN9ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050245570-A1 | 4-carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines | DENINNO MICHAEL P | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245570-A1 | 4-carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines | CETP, APOB, HDLBP | KDM1A 3157/4885PDK2 2491/4885GPR119 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.