Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18406939 | 0.84 | PGR (0.54) | POLBGAAALDH1A1PGRLMNA | |
| SCHEMBL3255431 | 0.83 | PGR (0.50) | GAAALDH1A1PGRLMNAMAPK1 | |
| SCHEMBL27743150 | 0.82 | HPGD (0.62) | MAPTPOLBPKMGAAALDH1A1 | |
| SCHEMBL9326040 | 0.81 | PGR (0.51) | GAAALDH1A1PGRLMNAMAPK1 | |
| SCHEMBL18405763 | 0.80 | LMNA (0.50) | MAPTPOLBGAAALDH1A1PGR | |
| SCHEMBL11219309 | 0.80 | PGR (0.50) | GAAALDH1A1PGRLMNAMAPK1 | |
| SCHEMBL15116360 | 0.80 | PTPN1 (0.65) | MAPTPOLBPKMGAAALDH1A1 | |
| SCHEMBL8694612 | 0.78 | NPC1 (0.55) | MAPTGAAALDH1A1PGRLMNA | |
| SCHEMBL5947358 | 0.78 | PGR (0.49) | GAAALDH1A1PGRLMNAMAPK1 | |
| SCHEMBL28763235 | 0.78 | HTT (0.54) | POLBGAAPGRLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288369-A1 | Novel n-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same | DIGITAL BIOTECH CO., LTD. (KR) | 2005-12-29 | — | — | US | disclosed |
| CN-1034929-A | The preparation method of crystallization beta-lactam solvate | LILLY CO ELI (US) | 1989-08-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288369-A1 | Novel n-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same | HRH2, HRH4, NMUR2 | MAPT 2346/4885POLB 4309/4885PKM 3822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.