SCHEMBL6364465

SCHEMBL6364465

[NH]C(=O)Cc1nc2ccccc2[nH]1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.63
KDM4E B2RXH2 5/20 0.63
MAPT P10636 4/20 0.63
HSD17B10 Q99714 3/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
RAB9A P51151 4/20 0.60
NPC1 O15118 3/20 0.60
CHRM1 P11229 1/20 0.59
POLB P06746 2/20 0.56
DDAH1 O94760 1/20 0.56
LMNA P02545 2/20 0.56
TSHR P16473 2/20 0.56
TDP1 Q9NUW8 2/20 0.55
HTT P42858 2/20 0.54
GAA P10253 1/20 0.53
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
HPGD P15428 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL761148 0.84 CHRM1 (0.71) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL30343700 0.83 MAPT (0.63) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL6403010 0.83 ALDH1A1 (0.63) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL2207637 0.83 MAPT (0.63) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL10337354 0.83 ALDH1A1 (0.68) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
Hydrochloric Acid SCHEMBL2211742 0.81 ALDH1A1 (0.66) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL9670494 0.81 ALDH1A1 (0.67) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL5849893 0.80 MAPT (0.78) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL10035809 0.80 ALDH1A1 (0.64) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL5307911 0.79 KDM4E (0.74) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890705-B2 Silver halide photosensitive material and image-forming method using same FUJI PHOTO FILM CO., LTD. (JP) 2005-05-10 US disclosed
US-6828070-B2 Heat sensitive element FUJI PHOTO FILM CO., LTD. (JP) 2004-12-07 US disclosed
US-6746830-B2 CAPABLE OF RAPIDLY FORMING HIGH-QUALITY IMAGE EXCELLENT IN SHARPNESS, COLOR REPRODUCIBILITY AND OPTICAL READABILITY FUJI PHOTO FILM CO., LTD. (JP) 2004-06-08 US disclosed
US-20030186176-A1 Silver halide photosensitive material and image-forming method using heat-responsive-discolorable coloring composition FUJI PHOTO FILM CO., LTD. 2003-10-02 US disclosed
US-20030118952-A1 Silver halide photosensitive material and image-forming method using same FUJI PHOTO FILM CO., LTD. 2003-06-26 US disclosed
US-20020015903-A1 Photosensitive material comprising reversibly decolorable colored layer and image-forming method using same FUJI PHOTO FILM CO., LTD. 2002-02-07 US disclosed
US-4599301-A IMPROVED COLOR REPRODUCIBILITY FUJI PHOTO FILM CO., LTD. (JP) 1986-07-08 US disclosed