SCHEMBL6403010

SCHEMBL6403010

O=C(S)Cc1nc2ccccc2[nH]1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.63
KDM4E B2RXH2 5/20 0.63
MAPT P10636 4/20 0.63
HSD17B10 Q99714 3/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
RAB9A P51151 4/20 0.60
NPC1 O15118 3/20 0.60
CHRM1 P11229 1/20 0.59
POLB P06746 2/20 0.56
DDAH1 O94760 1/20 0.56
LMNA P02545 2/20 0.56
TSHR P16473 2/20 0.56
TDP1 Q9NUW8 2/20 0.55
HTT P42858 2/20 0.54
GAA P10253 1/20 0.53
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
HPGD P15428 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7732696 0.84 DDAH1 (0.58) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL761148 0.84 CHRM1 (0.71) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL2207637 0.83 MAPT (0.63) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL10337354 0.83 ALDH1A1 (0.68) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL30343700 0.83 MAPT (0.63) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL6364465 0.83 ALDH1A1 (0.63) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL9670494 0.81 ALDH1A1 (0.67) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
Hydrochloric Acid SCHEMBL2211742 0.81 ALDH1A1 (0.66) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL5849893 0.80 MAPT (0.78) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL10035809 0.80 ALDH1A1 (0.64) ALDH1A1KDM4EMAPTHSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919389-B2 Polymer compositions containing benzimidazole based stabilizer compounds CROMPTON CORPORATION (US) 2005-07-19 US disclosed
US-20040180995-A1 Polymer compositions containing benzimidazole based stabilizer compounds ADDIVANT USA, LLC 2004-09-16 US disclosed
US-4612049-A BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed
US-4391886-A Methine colorant materials and the use thereof in electrophoretic migration imaging layers and processes EASTMAN KODAK COMPANY (US) 1983-07-05 US disclosed
US-4304908-A Methine colorant materials and the use thereof in electrophoretic migration imaging layers and processes EASTMAN KODAK COMPANY (US) 1981-12-08 US disclosed
EP-0006347-A1 Compositions and method for regulating soybean plant growth utilizing substituted benzazolylthioalkanoic acids MONSANTO COMPANY (US) 1980-01-09 EP disclosed