⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6363838 | 0.98 | ALDH1A1 (0.30) | — | |
| SCHEMBL6364837 | 0.95 | ALDH1A1 (0.32) | — | |
| SCHEMBL6364958 | 0.92 | ALDH1A1 (0.32) | — | |
| SCHEMBL6364884 | 0.86 | ALDH1A1 (0.32) | — | |
| SCHEMBL6364960 | 0.83 | ALDH1A1 (0.33) | — | |
| SCHEMBL6364650 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL6370802 | 0.80 | ALDH1A1 (0.30) | — | |
| SCHEMBL6363661 | 0.72 | ALDH1A1 (0.34) | — | |
| SCHEMBL6365233 | 0.72 | TYMP (0.31) | — | |
| SCHEMBL6553111 | 0.71 | TYMP (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176941-A1 | Nucleoside analogues whose sugar moieties are bound in s-form and oligonucleotide derivatives comprising nucleotide analogues thereof | TAKESHI IMANISHI (JP) | 2005-08-11 | — | — | US | disclosed |
| EP-1486504-A1 | NUCLEOSIDE ANALOGUES WHOSE SUGAR MOIETIES ARE BOUND IN S-FORM AND OLIGONUCLEOTIDE DERIVATIVES COMPRISING NUCLEOTIDE ANALOGUES THEREOF | Imanishi, Takeshi (JP) | 2004-12-15 | — | — | EP | disclosed |