Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6365233 | 0.84 | TYMP (0.31) | — | |
| SCHEMBL6363661 | 0.83 | ALDH1A1 (0.34) | ALDH1A1BRD4 | |
| SCHEMBL6363838 | 0.81 | ALDH1A1 (0.30) | ALDH1A1BRD4 | |
| SCHEMBL6364648 | 0.80 | — | — | |
| SCHEMBL6364837 | 0.80 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL6364884 | 0.79 | ALDH1A1 (0.32) | ALDH1A1BRD4 | |
| SCHEMBL6358756 | 0.76 | ALDH1A1 (0.34) | ALDH1A1BRD4 | |
| SCHEMBL6553111 | 0.76 | TYMP (0.32) | — | |
| SCHEMBL6364958 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL7788368 | 0.73 | PDE4D (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176941-A1 | Nucleoside analogues whose sugar moieties are bound in s-form and oligonucleotide derivatives comprising nucleotide analogues thereof | TAKESHI IMANISHI (JP) | 2005-08-11 | — | — | US | disclosed |
| EP-1486504-A1 | NUCLEOSIDE ANALOGUES WHOSE SUGAR MOIETIES ARE BOUND IN S-FORM AND OLIGONUCLEOTIDE DERIVATIVES COMPRISING NUCLEOTIDE ANALOGUES THEREOF | Imanishi, Takeshi (JP) | 2004-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176941-A1 | Nucleoside analogues whose sugar moieties are bound in s-form and oligonucleotide derivatives comprising nucleotide analogues thereof | RNGTT, NSUN2, SNRPE | ALDH1A1 951/4885BRD4 3800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.