Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6078781 | 0.77 | KDM4E (0.40) | — | |
| SCHEMBL14444100 | 0.74 | IDO1 (0.61) | — | |
| SCHEMBL10891775 | 0.72 | SLC6A2 (0.61) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4729314 | 0.72 | NR4A2 (0.60) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4443897 | 0.70 | TDP1 (0.47) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6364667 | 0.69 | CYP1A2 (0.44) | — | |
| SCHEMBL1549844 | 0.68 | NR4A2 (0.62) | — | |
| SCHEMBL14601979 | 0.64 | SLC6A3 (0.71) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL13060552 | 0.64 | SLC6A3 (0.71) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL14602065 | 0.64 | SLC6A3 (0.71) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178953-B1 | AROMATIC AMIDES | WARNER LAMBERT CO (US) | 2003-12-03 | — | — | EP | claimed |
| JP-2002544186-A | — | — | 2002-12-24 | — | — | JP | claimed |
| CN-1352631-A | Aromatic amides | WARNER LAMBERT CO (US) | 2002-06-05 | — | — | CN | claimed |
| EP-1178953-A1 | AROMATIC AMIDES | WARNER-LAMBERT COMPANY (US) | 2002-02-13 | — | — | EP | claimed |
| WO-2000068184-A1 | AROMATIC AMIDES | WARNER-LAMBERT COMPANY (US) | 2000-11-16 | — | — | WO | claimed |
| US-6846953-B1 | Aromatic amides | WARNER LAMBERT COMPANY (US) | 2005-01-25 | — | — | US | disclosed |