Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3503674 | 0.79 | MAPT (0.43) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL6364613 | 0.74 | AKT1 (0.35) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL27641444 | 0.71 | NPC1 (0.37) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL27762382 | 0.69 | NPC1 (0.40) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL27741902 | 0.69 | BCHE (0.39) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL372312 | 0.69 | MAPT (0.40) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL10425119 | 0.68 | MAPT (0.45) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL1938587 | 0.68 | NPC1 (0.41) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL28150514 | 0.67 | NPC1 (0.43) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL27741901 | 0.67 | NPC1 (0.40) | MAPTBCHENPC1RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050031572-A1 | Cosmetic or dermatological preparations including hops or hop-malt extracts and methods of using same for the prophylaxis and treatment of skin symptoms | BEIERSDORF AG | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050031572-A1 | Cosmetic or dermatological preparations including hops or hop-malt extracts and methods of using same for the prophylaxis and treatment of skin symptoms | CUTA, TYR, HMBS | MAPT 438/4885BCHE 1312/4885NPC1 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.