Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 19/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14100410 | 0.89 | LTA4H (0.53) | LTA4HKCNH2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4689574 | 0.87 | LTA4H (0.51) | LTA4HKCNH2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4707568 | 0.86 | LTA4H (0.50) | LTA4HKCNH2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4708925 | 0.85 | LTA4H (0.49) | LTA4HKCNH2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4707880 | 0.84 | CYP1A2 (0.53) | LTA4HKCNH2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6362525 | 0.82 | LTA4H (0.53) | LTA4HKCNH2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4695933 | 0.80 | LTA4H (0.56) | LTA4HKCNH2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4709249 | 0.80 | LTA4H (0.45) | LTA4HKCNH2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4708273 | 0.78 | LTA4H (0.55) | LTA4HKCNH2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2169641 | 0.78 | LTA4H (0.62) | LTA4HKCNH2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043379-A1 | LTA4H Modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043379-A1 | LTA4H Modulators | LTA4H, LTB4R, LTB4R2 | LTA4H 1/4885KCNH2 3429/4885CYP1A2 1019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.