Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | LTK | P29376 | 1/20 | 0.48 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370234 | 0.90 | POLB (0.50) | IDO1CHEK1PIM1LTKLIMK1 | |
| SCHEMBL6365165 | 0.84 | IDO1 (0.68) | IDO1CHEK1PIM1LTKLIMK1 | |
| SCHEMBL18949757 | 0.81 | NCF1 (0.54) | NCF1IDO1CHEK1PIM1LTK | |
| SCHEMBL6365362 | 0.78 | IDO1 (0.57) | IDO1CHEK1PIM1LTKLIMK1 | |
| SCHEMBL16019538 | 0.78 | NCF1 (0.47) | NCF1IDO1CHEK1PIM1LTK | |
| Hydrochloric Acid SCHEMBL9850513 | 0.77 | CYP1A2 (0.48) | IDO1CHEK1PIM1LTKLIMK1 | |
| SCHEMBL11669132 | 0.76 | CA12 (0.61) | NCF1SLC2A1ALDH1A1GAASLC40A1 | |
| SCHEMBL18949717 | 0.75 | NCF1 (0.50) | NCF1IDO1CHEK1PIM1LTK | |
| Hydrochloric Acid SCHEMBL11668772 | 0.75 | ALDH1A1 (0.62) | NCF1SLC2A1ALDH1A1GAAALPG | |
| SCHEMBL6671719 | 0.73 | MALT1 (0.54) | ALDH1A1NPSR1TOP2APOLBRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846953-B1 | Aromatic amides | WARNER LAMBERT COMPANY (US) | 2005-01-25 | — | — | US | claimed |
| EP-1178953-B1 | AROMATIC AMIDES | WARNER LAMBERT CO (US) | 2003-12-03 | — | — | EP | claimed |
| JP-2002544186-A | — | — | 2002-12-24 | — | — | JP | claimed |
| CN-1352631-A | Aromatic amides | WARNER LAMBERT CO (US) | 2002-06-05 | — | — | CN | claimed |
| EP-1178953-A1 | AROMATIC AMIDES | WARNER-LAMBERT COMPANY (US) | 2002-02-13 | — | — | EP | claimed |
| WO-2000068184-A1 | AROMATIC AMIDES | WARNER-LAMBERT COMPANY (US) | 2000-11-16 | — | — | WO | claimed |
| US-6846953-B1 | Aromatic amides | WARNER LAMBERT COMPANY (US) | 2005-01-25 | — | — | US | disclosed |