Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837515 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPK1LMNAALDH1A1MEN1 | |
| SCHEMBL13373558 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2POLBMAPK1TDP1FAAH | |
| SCHEMBL1233306 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBMAPK1TDP1FAAH | |
| Bicarbonate SCHEMBL2360581 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2POLBMAPK1TDP1FAAH | |
| SCHEMBL11283595 | 0.73 | MAPT (0.47) | SMN1; SMN2POLBMAPK1LMNAALDH1A1 | |
| SCHEMBL14357208 | 0.73 | MAPK1 (0.65) | SMN1; SMN2POLBMAPK1TDP1FAAH | |
| SCHEMBL26596748 | 0.73 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBMAPK1TDP1FAAH | |
| SCHEMBL2227637 | 0.73 | SMN1; SMN2 (0.64) | SMN1; SMN2POLBMAPK1TDP1FAAH | |
| SCHEMBL7272333 | 0.72 | MAPT (0.47) | SMN1; SMN2POLBMAPK1LMNAALDH1A1 | |
| SCHEMBL13373542 | 0.72 | SMN1; SMN2 (0.56) | SMN1; SMN2POLBMAPK1TDP1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032777-A1 | Diazacycloalkanes as oxytocin agonists | FEERING B.V. (NL) | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032777-A1 | Diazacycloalkanes as oxytocin agonists | OXTR, GNRHR, KISS1R | SMN1; SMN2 1677/4885POLB 3801/4885MAPK1 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.