Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | NSD2 | O96028 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.43 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.38 |
| ▸ | S100A10 | P60903 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27602051 | 0.95 | MAPK1 (0.64) | MAPTMAPK1NSD2KDM4EADORA2A | |
| SCHEMBL10608055 | 0.95 | MAPT (0.69) | MAPTMAPK1NSD2KDM4EADORA2A | |
| SCHEMBL10608058 | 0.84 | MAPT (0.51) | MAPTMAPK1NSD2KDM4EADORA2A | |
| SCHEMBL6365480 | 0.83 | MAPK1 (0.64) | MAPTMAPK1NSD2KDM4EADORA2A | |
| SCHEMBL14039788 | 0.82 | MAPT (0.73) | MAPTMAPK1NSD2KDM4EADORA2A | |
| SCHEMBL4465042 | 0.80 | MAPT (0.89) | MAPTMAPK1NSD2KDM4EADORA2A | |
| SCHEMBL11579534 | 0.80 | MAPT (0.75) | MAPTMAPK1NSD2KDM4EADORA2A | |
| SCHEMBL10606990 | 0.80 | KDM4E (0.56) | MAPTMAPK1NSD2KDM4EADORA2A | |
| SCHEMBL28752267 | 0.79 | MAPK1 (0.68) | MAPTMAPK1NSD2KDM4EADORA2A | |
| SCHEMBL17284185 | 0.78 | MAPK1 (0.72) | MAPTMAPK1NSD2KDM4EADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | HUANG HSU-SHAN (TW) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | NFE2L2, NR2F2, TFAM | MAPT 4766/4885MAPK1 4421/4885NSD2 2666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.