Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24775484 | 0.81 | ALDH1A1 (0.43) | MAOBMAOAGAAKDM4EALDH1A1 | |
| SCHEMBL18729770 | 0.81 | CHRNB2 (0.49) | GAAKDM4ECYP2D6OPRM1OPRD1 | |
| SCHEMBL17130333 | 0.81 | CHRNB2 (0.49) | GAAKDM4ECYP2D6OPRM1OPRD1 | |
| SCHEMBL18751620 | 0.81 | CHRNB2 (0.49) | GAAKDM4ECYP2D6OPRM1OPRD1 | |
| SCHEMBL9963125 | 0.81 | ALDH1A1 (0.43) | MAOBMAOAGAAKDM4EALDH1A1 | |
| SCHEMBL18751622 | 0.76 | CYP2D6 (0.41) | MAOBMAOAKDM4ECYP2D6OPRM1 | |
| SCHEMBL9965914 | 0.76 | ALDH1A1 (0.45) | MAOBMAOAGAAKDM4EALDH1A1 | |
| SCHEMBL18768490 | 0.76 | KDM4E (0.39) | KDM4ECYP2D6OPRM1OPRD1OPRK1 | |
| SCHEMBL17114338 | 0.75 | CYP2D6 (0.40) | KDM4ECYP2D6OPRM1OPRD1OPRK1 | |
| SCHEMBL17114337 | 0.75 | CYP2D6 (0.40) | KDM4ECYP2D6OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419433-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010120621-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-21 | — | — | WO | disclosed |