Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SCSF1RDRD2FLT1FLT3FLT4HTR1BHTR1DHTR1FKDRKITMETOPRD1OPRK1OPRM1PDGFRAPDGFRBRET
The experimentally established mechanism targets of Malic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malic Acid SCHEMBL6372959 | 0.93 | CA4 (0.57) | CA4CA1NFKB1CA2GPR84 | |
| SCHEMBL6072518 | 0.82 | CA2 (0.47) | CA4CA1NFKB1CA2GPR84 | |
| Malic Acid SCHEMBL3593174 | 0.81 | CA4 (0.94) | CA4NFKB1CA2SLC22A16CYP3A4 | |
| L-Lactic Acid SCHEMBL6072253 | 0.79 | CA1 (0.48) | CA1NFKB1CA2GPR84CYP3A4 | |
| Malic Acid SCHEMBL29359514 | 0.79 | CA4 (0.59) | CA4CA1NFKB1CA2GPR84 | |
| Malic Acid SCHEMBL511412 | 0.79 | CA4 (0.59) | CA4CA1NFKB1CA2GPR84 | |
| Tetrabuthylammonium SCHEMBL5874718 | 0.79 | CA4 (0.59) | CA4CA1NFKB1 | |
| SCHEMBL6072819 | 0.77 | CA1 (0.50) | CA1NFKB1CA2CYP3A4TSHR | |
| Malic Acid SCHEMBL27944022 | 0.77 | CA4 (0.81) | CA4CA1NFKB1CA2SLC22A16 | |
| Malic Acid SCHEMBL674352 | 0.77 | CA4 (0.55) | CA4CA1NFKB1CA2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4741462-A1 | PLASTICIZER COMPOSITION | Kao Corporation (JP) | 2026-05-13 | — | — | EP | disclosed |
| EP-4682199-A1 | MEMBER, AND SEMICONDUCTOR MANUFACTURING?RELATED DEVICE | Daikin Industries, Ltd. (JP) | 2026-01-21 | — | — | EP | disclosed |
| US-12486215-B2 | Method of manufacturing diester-based compound | LG CHEM, LTD. (KR) | 2025-12-02 | — | — | US | disclosed |
| CN-118184509-A | Process for producing diester compound | 株式会社LG化学 | 2024-06-14 | — | — | CN | disclosed |
| CN-114829334-B | Process for producing diester compound | 株式会社LG化学 | 2024-04-02 | — | — | CN | disclosed |
| US-20230348355-A1 | METHOD OF MANUFACTURING DIESTER-BASED COMPOUND | LG CHEM, LTD. (KR) | 2023-11-02 | — | — | US | disclosed |
| US-20230290550-A1 | MAGNETIC RESIN COMPOSITION FOR INJECTION MOLDING, AND INJECTION MOLDED BODY FOR MAGNETIC SHIELDS | TOYO INK SC HOLDINGS CO., LTD. (JP) | 2023-09-14 | — | — | US | disclosed |
| WO-2023120301-A1 | MAGNETIC RESIN COMPOSITION FOR INJECTION MOLDING, AND INJECTION-MOLDED ARTICLE FOR MAGNETIC SHIELD | 東洋インキＳＣホールディングス株式会社 | 2023-06-29 | — | — | WO | disclosed |
| US-20230150911-A1 | METHOD OF MANUFACTURING DIESTER-BASED COMPOUND | LG CHEM, LTD. (KR) | 2023-05-18 | — | — | US | disclosed |
| EP-4180485-A1 | MAGNETIC RESIN COMPOSITION FOR INJECTION MOLDING, AND INJECTION MOLDED BODY FOR MAGNETIC SHIELDS | Toyo Ink SC Holdings Co., Ltd. (JP) | 2023-05-17 | — | — | EP | disclosed |
| CN-114829334-A | Process for producing diester compound | 株式会社LG化学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114829335-A | Preparation method of diester material | 株式会社LG化学 | 2022-07-29 | — | — | CN | disclosed |
| EP-4032875-A1 | METHOD FOR PREPARING DIESTER COMPOUND | LG Chem, Ltd. (KR) | 2022-07-27 | — | — | EP | disclosed |
| EP-4023629-A1 | METHOD FOR PREPARING DIESTER COMPOUND | LG Chem, Ltd. (KR) | 2022-07-06 | — | — | EP | disclosed |
| CN-104011091-B | The manufacture method of chlorinated vinyl chloride-based resin | TOKUYAMA SEKISUI Co.,Ltd. (JP) | 2016-05-04 | — | — | CN | disclosed |
| CN-104011091-A | Method for producing chlorinated vinyl chloride-based resin | TOKUYAMA SEKISUI CO LTD | 2014-08-27 | — | — | CN | disclosed |
| US-20050107501-A1 | Compound resin molding and process for producing the same | SUZUKA FUJI XEROX CO., LTD. (JP) | 2005-05-19 | — | — | US | disclosed |
| EP-1466723-A1 | COMPOSITE RESIN MOLDING AND PROCESS FOR PRODUCING THE SAME | Suzuka Fuji Xerox Co., Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |