Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 4/20 | 0.39 |
| ▸ | CES1 | P23141 | 4/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL6072494 | 0.91 | CA1 (0.50) | CA1CA2NFKB1CES2CES1 | |
| SCHEMBL6072819 | 0.88 | CA1 (0.50) | CA1CA2NFKB1CYP3A4TSHR | |
| L-Lactic Acid SCHEMBL27740901 | 0.81 | CA1 (0.58) | CA1CA2NFKB1CES2CES1 | |
| SCHEMBL4192133 | 0.81 | CA1 (0.70) | CA1CA2NFKB1CYP3A4TSHR | |
| SCHEMBL6072518 | 0.81 | CA2 (0.47) | CA1CA2NFKB1CYP3A4TSHR | |
| Acetic Acid SCHEMBL674467 | 0.80 | CES1 (0.46) | CA1CA2CES2CES1GPR84 | |
| Oxalic Acid SCHEMBL1401946 | 0.80 | CA1 (0.46) | CA1CA2CES2CES1GPR84 | |
| SCHEMBL4196107 | 0.80 | CA1 (0.52) | CA1CA2CES2CES1GPR84 | |
| Malic Acid SCHEMBL6368134 | 0.79 | CA4 (0.61) | CA1CA2NFKB1CYP3A4TSHR | |
| SCHEMBL11883607 | 0.79 | CA1 (0.52) | CA1CA2NFKB1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516722-B1 | ACRYLIC RESIN COMPOSITION, ORGANOSILOXANE RESIN COMPOSITION AND LAMINATES MADE BY USING THEM | TEIJIN CHEMICALS LTD (JP) | 2015-09-02 | — | — | EP | disclosed |
| US-7070859-B2 | Acrylic resin composition organosiloxane resin composition and laminate comprising the same | TEIJIN CHEMICALS, LTD. (JP) | 2006-07-04 | — | — | US | disclosed |
| EP-1516722-A1 | ACRYLIC RESIN COMPOSITION, ORGANOSILOXANE RESIN COMPOSITION AND LAMINATES MADE BY USING THEM | Teijin Chemicals, Ltd. (JP) | 2005-03-23 | — | — | EP | disclosed |
| US-20040247878-A1 | Acrylic resin composition organosiloxane resin composition and laminate comprising the same | TEIJIN CHEMICALS LTD. (JP) | 2004-12-09 | — | — | US | disclosed |