SCHEMBL6368355

SCHEMBL6368355

COc1ccccc1C(=O)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
GAA P10253 1/20 0.62
HPGD P15428 2/20 0.59
TP53 P04637 1/20 0.59
GLA P06280 1/20 0.59
KMT2A Q03164 3/20 0.58
FPR2 P25090 2/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
CAPN1 P07384 2/20 0.56
CTSD P07339 1/20 0.55
ALOX15 P16050 1/20 0.55
KIFC1 Q9BW19 1/20 0.53
PSMB5 P28074 1/20 0.53
LMNA P02545 1/20 0.52
MEN1 O00255 1/20 0.52
POLB P06746 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29619793 1.00 ALDH1A1 (0.62) ALDH1A1GAAHPGDTP53GLA
SCHEMBL6368357 1.00 ALDH1A1 (0.62) ALDH1A1GAAHPGDTP53GLA
SCHEMBL28613885 0.90 HPGD (0.58) ALDH1A1GAAHPGDTP53GLA
SCHEMBL3857457 0.86 KMT2A (0.57) ALDH1A1GAAHPGDKMT2AL3MBTL1
SCHEMBL19248887 0.86 KIFC1 (0.53) ALDH1A1GAAKMT2AL3MBTL1KIFC1
SCHEMBL12984069 0.86 HPGD (0.61) ALDH1A1HPGDTP53GLAKMT2A
SCHEMBL9756269 0.86 HPGD (0.61) ALDH1A1HPGDTP53GLAKMT2A
SCHEMBL2794042 0.86 HPGD (0.61) ALDH1A1HPGDTP53GLAKMT2A
SCHEMBL8430824 0.84 HPGD (0.59) ALDH1A1GAAHPGDTP53GLA
SCHEMBL2327233 0.84 HPGD (0.59) ALDH1A1HPGDTP53GLAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067950-A1 MEANS AND METHODS FOR DETOXIFYING OCHRATOXIN A DSM Austria GmbH (AT) 2024-02-29 US disclosed
EP-4263826-A2 MEANS AND METHODS FOR DETOXIFYING OCHRATOXIN A DSM Austria GmbH (AT) 2023-10-25 EP disclosed
WO-2022129517-A2 MEANS AND METHODS FOR DETOXIFYING OCHRATOXIN A ERBER AKTIENGESELLSCHAFT (AT) 2022-06-23 WO disclosed
CN-114645037-A Means and methods for detoxification of ochratoxin A 艾尔柏股份公司 2022-06-21 CN disclosed
CN-106008665-B Compound with tumor proliferation inhibition function and preparation method and application thereof 北京大学 2021-03-16 CN disclosed
CN-107903185-B Preparation and application of novel eEF2K inhibitor 四川大学 2020-05-26 CN disclosed
WO-2020014726-A1 TREATMENT FOR LIVER REGENERATION XENEXUS PHARMACEUTICALS PTY. LTD. (AU) 2020-01-23 WO disclosed
US-6903075-B1 Heterocyclic amide compounds as cell adhesion inhibitors MERCK & CO., INC. (US) 2005-06-07 US disclosed